Pdpn Immunohistochemistry Gene Expression Assay

Gene Expression Data
Assay Details

Assay

Reference:	J:196288 Nechiporuk T, et al., Dlg5 maintains apical aPKC and regulates progenitor differentiation during lung morphogenesis. Dev Biol. 2013 May 15;377(2):375-84
Assay type:	Immunohistochemistry
MGI Accession ID:	MGI:6203010
Gene symbol:	Pdpn
Gene name:	podoplanin

Antibody:	Anti-Podoplanin (clone 8.1.1)
Detection system:	Secondary antibody coupled to fluorescein

Results

4C ©

4E ©

Specimen 4C: embryonic day 15.5 (more

)
Note: Double labeled: green - Pdpn; red - Sftpc (assay MGI:6203011).

Structure	Level	Pattern	Image	Note
TS23: lung epithelium	Present		4E , 4C	Apical localization of staining was seen in wild type.

4C' ©

4E' ©

Specimen 4C': embryonic day 15.5; Dlg5^tm1Vv/Dlg5^tm1Vv (more

)
Note: Double labeled: green - Pdpn; red - Sftpc (assay MGI:6203011).

Structure	Level	Pattern	Image	Note
TS23: lung epithelium	Present		4E' , 4C'	Expression levels were similar in mutant lung epithelium compared to wild type, but the staining failed to localize to the apical membrane domain in mutant cells.

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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