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Gene Expression Data
Assay Details
Assay
Reference: J:112915 Kruger M, et al., Functional redundancy of NSCL-1 and NeuroD during development of the petrosal and vestibulocochlear ganglia. Eur J Neurosci. 2006 Sep;24(6):1581-90
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6202107
Gene symbol: Tubb3
Gene name: tubulin, beta 3 class III
Results
Specimen 2C: embryonic day 18.5; Nhlh1tm1Thbr/Nhlh1+ (more )
Note: Double labeled: brown - Tubb3; blue - Nhlh1 reporter (assay MGI:6202083).
Structure Level Pattern Image Note
TS26: inner ear Present Regionally restricted 2C
Specimen 2C inset: embryonic day 18.5; Nhlh1tm1Thbr/Nhlh1+ (more )
Note: Double labeled: brown - Tubb3; blue - Nhlh1 reporter (assay MGI:6202083).
Structure Level Pattern Image Note
TS26: vestibulo-cochlear ganglion Present 2C inset
Specimen 2F: embryonic day 18.5; Nhlh1tm1Thbr/Nhlh1+ (more )
Note: Double labeled: brown - Tubb3; blue - Nhlh1 reporter (assay MGI:6202083).
Structure Level Pattern Image Note
TS26: vestibulo-cochlear ganglion Present Regionally restricted 2F
Specimen 2F inset: embryonic day 18.5; Nhlh1tm1Thbr/Nhlh1+ (more )
Note: Double labeled: brown - Tubb3; blue - Nhlh1 reporter (assay MGI:6202083).
Structure Level Pattern Image Note
TS26: organ of Corti Present 2F inset
Specimen 4D: embryonic day 10.5; Neurod1tm1Mjts/Neurod1+, Nhlh1tm1Thbr/Nhlh1+ (more )
Structure Level Pattern Image Note
TS17: trigeminal ganglion Present 4D
TS17: facial ganglion Present 4D Expression in geniculate ganglion.
TS17: acoustic ganglion Present 4D Expression in vestibulocochlear ganglion.
Specimen 4E: embryonic day 10.5; Neurod1tm1Mjts/Neurod1tm1Mjts, Nhlh1tm1Thbr/Nhlh1+ (more )
Structure Level Pattern Image Note
TS17: trigeminal ganglion Present 4E
TS17: facial ganglion Present 4E Expression in geniculate ganglion.
TS17: acoustic ganglion Trace 4E Authors report virtually no expression in vestibulocochlear ganglion.
Specimen 4F: embryonic day 10.5; Neurod1tm1Mjts/Neurod1tm1Mjts, Nhlh1tm1Thbr/Nhlh1tm1Thbr (more )
Structure Level Pattern Image Note
TS17: trigeminal ganglion Present 4F
TS17: facial ganglion Present 4F Expression in geniculate ganglion.
TS17: acoustic ganglion Trace 4F Authors report virtually no expression in vestibulocochlear ganglion.
Specimen 4H: embryonic day 10.5; Nhlh1tm1Thbr/Nhlh1tm1Thbr (more )
Structure Level Pattern Image Note
TS17: trigeminal ganglion Present 4H Authors report expression not affected in mutant.
TS17: facial ganglion Present 4H Authors report expression in geniculate ganglion not affected in mutant.
TS17: acoustic ganglion Present 4H Expression in vestibulocochlear ganglion.
TS17: glossopharyngeal ganglion Weak Regionally restricted 4H Significant reduction in expression in in petrosal ganglion.
TS17: vagus ganglion Present Regionally restricted 4H Expression in nodose ganglion
Specimen 4I: embryonic day 10.5; Nhlh1tm1Thbr/Nhlh1tm1Thbr (more )
Structure Level Pattern Image Note
TS17: glossopharyngeal ganglion Weak Regionally restricted 4I Significant reduction in expression in in petrosal ganglion.
Specimen 4J: embryonic day 10.5; Neurod1tm1Mjts/Neurod1tm1Mjts, Nhlh1tm1Thbr/Nhlh1tm1Thbr (more )
Structure Level Pattern Image Note
TS17: trigeminal ganglion Present 4J Authors report expression not affected in mutant.
TS17: facial ganglion Present 4J Authors report expression in geniculate ganglion not affected in mutant.
TS17: glossopharyngeal ganglion Weak Regionally restricted 4J Significant reduction in expression in in petrosal ganglion.
TS17: vagus ganglion Present Regionally restricted 4J Expression in nodose ganglion
Specimen 4K: embryonic day 10.5; Neurod1tm1Mjts/Neurod1tm1Mjts, Nhlh1tm1Thbr/Nhlh1tm1Thbr (more )
Structure Level Pattern Image Note
TS17: glossopharyngeal ganglion Weak Regionally restricted 4K Significant reduction in expression in in petrosal ganglion.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory