Gene Expression Data
Assay Details
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Assay
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Reference:
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J:191045
Huebner AJ, et al., Amniotic fluid activates the nrf2/keap1 pathway to repair an epidermal barrier defect in utero. Dev Cell. 2012 Dec 11;23(6):1238-46
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Assay type:
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Immunohistochemistry
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MGI Accession ID:
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MGI:6200430
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Gene symbol:
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Nfe2l2
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Gene name:
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nuclear factor, erythroid derived 2, like 2
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Antibody:
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Anti-Nrf2
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Detection system:
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Biotinylated secondary antibody/[Strept]avidin coupled to horseradish peroxidase
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Results
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Specimen
1D wt:
embryonic day 16.5
(more  )
Specimen
1D wt:
(close  )
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Genetic Background:
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Not Specified
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Age:
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embryonic day 16.5
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Sex:
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Not Specified
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Type:
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section
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Embedding:
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Paraffin
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| Structure |
Level |
Pattern |
Image |
Note |
| TS24: epidermis |
Present |
Regionally restricted |
1D wt
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Expression was detected in dorsal epidermis.
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Specimen
1D LKO:
(close )
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Genetic Background:
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involves: 129S7/SvEvBrd
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Mutant Allele(s):
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Loricrintm1Der/Loricrintm1Der
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Age:
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embryonic day 16.5
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Sex:
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Not Specified
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Type:
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section
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Embedding:
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Paraffin
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| Structure |
Level |
Pattern |
Image |
Note |
| TS24: epidermis |
Present |
Regionally restricted |
1D LKO
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Ectopic nuclear expression was noted in the suprabasal layers of the epidermis of the mutant.
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Specimen
1E wt:
embryonic day 17.5
(more )
Specimen
1E wt:
(close )
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Genetic Background:
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Not Specified
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Age:
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embryonic day 17.5
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Sex:
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Not Specified
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Type:
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section
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Embedding:
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Paraffin
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| Structure |
Level |
Pattern |
Image |
Note |
| TS25: epidermis |
Present |
Regionally restricted |
1E wt
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Expression was detected in dorsal epidermis.
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Specimen
1E ft/ft:
embryonic day 17.5; Flgft/ Flgft
(more )
Specimen
1E ft/ft:
(close )
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Genetic Background:
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Not Specified
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Mutant Allele(s):
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Flgft/Flgft
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Age:
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embryonic day 17.5
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Sex:
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Not Specified
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Type:
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section
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Embedding:
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Paraffin
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| Structure |
Level |
Pattern |
Image |
Note |
| TS25: epidermis |
Present |
Regionally restricted |
1E ft/ft
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Pronounced nuclear expression was noted in the suprabasal layers of the epidermis of the mutant.
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Specimen
S1D wt E14.5:
embryonic day 14.5
(more )
Specimen
S1D wt E14.5:
(close )
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Genetic Background:
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Not Specified
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Age:
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embryonic day 14.5
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Sex:
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Not Specified
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Type:
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section
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Embedding:
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Paraffin
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| Structure |
Level |
Pattern |
Image |
Note |
| TS22: epidermis |
Present |
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S1D wt E14.5
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Nuclear staining was not observed.
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Specimen
S1D LKO E14.5:
(close )
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Genetic Background:
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involves: 129S7/SvEvBrd
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Mutant Allele(s):
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Loricrintm1Der/Loricrintm1Der
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Age:
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embryonic day 14.5
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Sex:
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Not Specified
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Type:
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section
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Embedding:
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Paraffin
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| Structure |
Level |
Pattern |
Image |
Note |
| TS22: epidermis |
Present |
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S1D LKO E14.5
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Nuclear staining was not observed. No difference in staining was noted between wild type and LKO mice.
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Specimen
S1D wt E15.5:
embryonic day 15.5
(more )
Specimen
S1D wt E15.5:
(close )
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Genetic Background:
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Not Specified
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Age:
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embryonic day 15.5
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Sex:
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Not Specified
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Type:
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section
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Embedding:
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Paraffin
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| Structure |
Level |
Pattern |
Image |
Note |
| TS23: epidermis |
Present |
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S1D wt E15.5
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Nuclear staining was not observed.
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Specimen
S1D LKO E15.5:
(close )
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Genetic Background:
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involves: 129S7/SvEvBrd
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Mutant Allele(s):
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Loricrintm1Der/Loricrintm1Der
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Age:
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embryonic day 15.5
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Sex:
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Not Specified
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Type:
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section
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Embedding:
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Paraffin
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| Structure |
Level |
Pattern |
Image |
Note |
| TS23: epidermis |
Present |
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S1D LKO E15.5
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Nuclear staining was not observed. No difference in staining was noted between wild type and LKO mice.
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Analysis Tools