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Gene Expression Data
Assay Details
Assay
Reference: J:146147 Espinoza-Lewis RA, et al., Shox2 is essential for the differentiation of cardiac pacemaker cells by repressing Nkx2-5. Dev Biol. 2009 Mar 15;327(2):376-85
Assay type: RNA in situ
MGI Accession ID: MGI:6200249
Gene symbol: Hcn4
Gene name: hyperpolarization-activated, cyclic nucleotide-gated K+ 4
Probe: Hcn4 probe4
Probe preparation: Antisense RNA
Results
Specimen 3A: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: sinoatrial node Present 3A
Specimen 3B: embryonic day 10.5; Shox2tm1Ypc/Shox2tm1Ypc (more )
Structure Level Pattern Image Note
TS17: sinoatrial node Present 3B Authors report expression in sinoatrial node (SAN) remained unchanged in mutant at E10.5.
Specimen 3C: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: sinoatrial node Present 3C
Specimen 3D: embryonic day 11.5; Shox2tm1Ypc/Shox2tm1Ypc (more )
Structure Level Pattern Image Note
TS19: sinoatrial node Trace 3D Expression severely reduced or absent in the mutant.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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05/28/2024
MGI 6.13 		The Jackson Laboratory