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Gene Expression Data
Assay Details
Assay
Reference: J:208091 Richardson RJ, et al., AMACO Is a Component of the Basement Membrane-Associated Fraser Complex. J Invest Dermatol. 2014 May;134(5):1313-22
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6199606
Gene symbol: Fras1
Gene name: Fraser extracellular matrix complex subunit 1
Antibody: anti-Fras1
Detection system: Secondary antibody coupled to colloidal gold
Assay notes: Size of the gold particles: 6nm.
Results
Specimen 3a/b: postnatal newborn (more )
Note: Double labeled: 6-nm gold - Fras1; 10-nm gold - Vwa2 (assay MGI:6199604).
Structure Level Pattern Image Note
TS27: dermis Present Regionally restricted 3b , 3a Expressed in distinct regions, anchoring plaques, in the dermis close to the basement membrane. Stained patches often occurred where anchoring fibrils fuse. Mostly colocalized with Vwa2.
Specimen 3c: postnatal newborn (more )
Note: Double labeled: 6-nm gold - Fras1; 10-nm gold - Col17a1 (assay MGI:6199614).
Structure Level Pattern Image Note
TS27: dermis Present Regionally restricted 3c Expressed in distinct regions, anchoring plaques, in the dermis close to the basement membrane. Stained patches often occurred where anchoring fibrils fuse. Collagen VII and Fras1 often occur at opposite sides of anchoring plaques.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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12/17/2024
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