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Gene Expression Data
Assay Details
Assay
Reference: J:143541 Chen L, et al., Rac1 deficiency in the forebrain results in neural progenitor reduction and microcephaly. Dev Biol. 2009 Jan 1;325(1):162-70
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6197794
Gene symbol: Casp3
Gene name: caspase 3
Antibody: anti-cleaved Caspase3
Detection system: Biotinylated secondary antibody/[Strept]avidin coupled to horseradish peroxidase
Results
Specimen 4A: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: telencephalon ventricular layer Present Regionally restricted 4A Expression mainly near and outside the subventricular border in the ventral telencephalon
Specimen 4B: embryonic day 14.5; Rac1tm1Djk/Rac1tm1Djk, Foxg1tm1(cre)Skm/Foxg1+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS22: telencephalon ventricular layer Present 4B Authors report increased expression in mutant compared to control embryos, most evident at E14.5
Specimen E14.5 Rac1-KO not shown: embryonic day 14.5; Rac1tm1Djk/Rac1tm1Djk, Foxg1tm1(cre)Skm/Foxg1+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS22: lateral ganglionic eminence mantle zone Present Regionally restricted Expression at subventricular zone-mantle zone border of lateral ganglionic eminence.
TS22: lateral ganglionic eminence subventricular zone Present Regionally restricted Expression at subventricular zone-mantle zone border of lateral ganglionic eminence.
Specimen E16.5 Control not shown: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: forebrain Present
Specimen E16.5 Rac1-KO not shown: embryonic day 16.5; Rac1tm1Djk/Rac1tm1Djk, Foxg1tm1(cre)Skm/Foxg1+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS24: forebrain Present Authors report increased expression in mutant compared to control embryos.
Specimen E18.5 Control not shown: embryonic day 18.5 (more )
Structure Level Pattern Image Note
TS26: forebrain Present
Specimen E18.5 Rac1-KO not shown: embryonic day 18.5; Rac1tm1Djk/Rac1tm1Djk, Foxg1tm1(cre)Skm/Foxg1+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS26: forebrain Present Authors report increased expression in mutant compared to control embryos.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/24/2026
MGI 6.24 		The Jackson Laboratory