Shmt2 Western blot Gene Expression Assay

Gene Expression Data
Assay Details

Assay

Reference:	J:259713 Tani H, et al., Mice deficient in the Shmt2 gene have mitochondrial respiration defects and are embryonic lethal. Sci Rep. 2018 Jan 11;8(1):425
Assay type:	Western blot
MGI Accession ID:	MGI:6197691
Gene symbol:	Shmt2
Gene name:	serine hydroxymethyltransferase 2 (mitochondrial)

Antibody:	SHMT2 antibody (12762)
Detection system:	Secondary antibody coupled to horseradish peroxidase

Results

	Sample Information		Bands	Other Sample Information
Lane	Age	Structure	Size Not Specified	Genetic Background	Mutant Allele(s)	Sex
+/+	E13.5	TS21: embryo	Present	Not Specified		Not Specified
m/+	E13.5	TS21: embryo	Present (a)	involves: C57BL/6JJcl	Shmt2^em1Jiha/Shmt2⁺	Not Specified
m/m	E13.5	TS21: embryo	Weak (b)	involves: C57BL/6JJcl	Shmt2^em1Jiha/Shmt2^em1Jiha	Not Specified

Notes:
(a) Protein levels were approximatrely half of wild-type.
(b) The authors state that low levels of protein were seen probably due to contaminating maternal cells, such as placenta or blood cells.

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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