About   Help   FAQ
Gene Expression Data
Assay Details
Assay
Reference: J:211921 McKeown CR, et al., Tropomyosin is required for cardiac morphogenesis, myofibril assembly, and formation of adherens junctions in the developing mouse embryo. Dev Dyn. 2014 Jun;243(6):800-17
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6192669
Gene symbol: Actn2
Gene name: actinin alpha 2
Results
Specimen 7B/C: embryonic day 8.5 (more )
Note: Double labeled: red - Actn2; green - Myom1 (assay MGI:6192671).`
Structure Level Pattern Image Note
TS13: cardiac muscle tissue Present Regionally restricted 7B , 7C Expression in cardiomyocytes.

Specimen 7E/F: embryonic day 8.5; Tpm1tm1Dfw/Tpm1tm1Dfw (more )
Note: Double labeled: red - Actn2; green - Myom1 (assay MGI:6192671).`
Structure Level Pattern Image Note
TS13: cardiac muscle tissue Present Regionally restricted 7F , 7E Expression in cardiomyocytes.

Specimen 7G/I: embryonic day 8.5 (more )
Note: Double labeled: red - Actn2; green - Myom1 (assay MGI:6192671).`
Structure Level Pattern Image Note
TS13: cardiac muscle tissue Present Regionally restricted 7G , 7I Expression at Z-lines of striated myofibrils.

Specimen 7J/L: embryonic day 8.5; Tpm1tm1Dfw/Tpm1tm1Dfw (more )
Note: Double labeled: red - Actn2; green - Myom1 (assay MGI:6192671).`
Structure Level Pattern Image Note
TS13: cardiac muscle tissue Present Regionally restricted 7J , 7L Expression in puncta in F-actin fibrils.

Specimen 8C/D: embryonic day 8.5 (more )
Note: Double labeled: red - Actn2; green - Tmod1 (assay MGI:6192673).`
Structure Level Pattern Image Note
TS13: cardiac muscle tissue Present Regionally restricted 8D , 8C Expression in cardiomyocytes in outer wall of heart in stripes at Z-lines in typical striated myofibrils.

Specimen 8G/H: embryonic day 8.5; Tpm1tm1Dfw/Tpm1tm1Dfw (more )
Note: Double labeled: red - Actn2; green - Tmod1 (assay MGI:6192673).`
Structure Level Pattern Image Note
TS13: cardiac muscle tissue Present Regionally restricted 8G , 8H Expression in cardiomyocytes in outer wall of heart in non-striated F-actin fibrillar structures.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
04/23/2024
MGI 6.23
The Jackson Laboratory