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Gene Expression Data
Assay Details
Assay
Reference: J:132608 Waimey KE, et al., Plexin-A3 and plexin-A4 restrict the migration of sympathetic neurons but not their neural crest precursors. Dev Biol. 2008 Mar 15;315(2):448-58
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6191716
Gene symbol: Ngfr
Gene name: nerve growth factor receptor (TNFR superfamily, member 16)
Antibody: anti-p75
Detection system: Secondary antibody coupled to Alexa Fluor 488
Results
Specimen 3I: embryonic day 9.5 (more )
Structure Level Pattern Image Note
TS15: migrating neural crest Present Regionally restricted 3I Expression in cells migrating segmentally through the rostral sclerotomes, avoiding the caudal.
Specimen 3J: embryonic day 9.5; Nrp2tm1Ddg/Nrp2tm1Ddg (more )
Structure Level Pattern Image Note
TS15: migrating neural crest Present Regionally restricted 3J Authors report the rostral migration pattern is lost in Npn2 mutants.
Specimen 3K: embryonic day 9.5; Plxna3tm1Matl/Plxna3tm1Matl, Plxna4tm1Matl/Plxna4tm1Matl (more )
Structure Level Pattern Image Note
TS15: migrating neural crest Present Regionally restricted 3K Authors report double mutants do not exhibit neural crest migration effects.
Specimen 3N: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: sympathetic nervous system Present Regionally restricted 3N Expression in cells forming discrete aggregates at the dorsal aorta.
Specimen 3O: embryonic day 10.5; Plxna3tm1Matl/Plxna3tm1Matl, Plxna4tm1Matl/Plxna4tm1Matl (more )
Structure Level Pattern Image Note
TS17: sympathetic nervous system Present Regionally restricted 3O Authors report normal aggregation occurs in double mutants; no ectopic cells are seen.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
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