Gene Expression Data
Assay Details
Assay
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Reference:
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J:131010
Kameda Y, et al., FRS2 alpha 2F/2F mice lack carotid body and exhibit abnormalities of the superior cervical sympathetic ganglion and carotid sinus nerve. Dev Biol. 2008 Feb 1;314(1):236-47
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Assay type:
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Immunohistochemistry
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MGI Accession ID:
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MGI:6189179
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Gene symbol:
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Chga
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Gene name:
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chromogranin A
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Antibody:
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anti-Chromogranin A
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Detection system:
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Biotinylated secondary antibody/[Strept]avidin coupled to horseradish peroxidase
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Assay notes:
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Fixation was Bouin's or 8% paraformaldehyde.
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Results
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Specimen
4D:
(close )
Genetic Background:
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involves: 129S/SvEv * Swiss Webster
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Mutant Allele(s):
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Frs2tm1Schl/Frs2tm1Schl
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Age:
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embryonic day 18.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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Other - See Notes
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Embedding:
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Paraffin
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Structure |
Level |
Pattern |
Image |
Note |
TS26: superior cervical ganglion |
Present |
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4D
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TS26: carotid body |
Present |
Regionally restricted |
4D
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Authors report expression in glomus cells dispersed in the wall of the common carotid artery where baroreceptors were distributed and sympathetic ganglion abutted.
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