Gene Expression Data
Assay Details
Assay
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Reference:
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J:216507
Chervenak AP, et al., The role of Zic genes in inner ear development in the mouse: Exploring mutant mouse phenotypes. Dev Dyn. 2014 Nov;243(11):1487-98
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Assay type:
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RNA in situ
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MGI Accession ID:
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MGI:6187912
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Gene symbol:
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Lfng
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Gene name:
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LFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
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Probe:
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Lfng cDNA8
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Probe preparation:
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Antisense labelled with digoxigenin RNA
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Results
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Specimen
9G:
embryonic day 10.5
(more )
Specimen
9G:
(close )
Genetic Background:
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129/SvEv
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Age:
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embryonic day 10.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Cryosection
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Specimen
9H:
embryonic day 10.5; Zic2Ku/Zic2 +
(more )
Specimen
9H:
(close )
Genetic Background:
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129S.CAnNCrl(C3)-Zic2Ku
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Mutant Allele(s):
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Zic2Ku/Zic2+
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Age:
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embryonic day 10.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Cryosection
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Specimen
9I:
(close )
Genetic Background:
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129S.CAnNCrl(C3)-Zic2Ku
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Mutant Allele(s):
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Zic2Ku/Zic2Ku
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Age:
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embryonic day 10.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Cryosection
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Structure |
Level |
Pattern |
Image |
Note |
TS17: inner ear epithelium |
Present |
Regionally restricted |
9I
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The region of expression in the otic epithelium of the mutant embryos appeared to have shifted laterally. However, authors indicate that taking the tilt of the otocyst in the mutant into consideration, the expression domain is indistinguishable from wild type. The expression also appears to be more extensive. Again authors suggest this may be due to phenotypic alterations of endolymphatic duct and sac development.
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