Casp3 Immunohistochemistry Gene Expression Assay - GXD

About Help FAQ

Gene Expression Data
Assay Details

Assay

Reference:	J:251322 Kim M, et al., DPP9 enzyme activity controls survival of mouse migratory tongue muscle progenitors and its absence leads to neonatal lethality due to suckling defect. Dev Biol. 2017 Nov 15;431(2):297-308
Assay type:	Immunohistochemistry
MGI Accession ID:	MGI:6163821
Gene symbol:	Casp3
Gene name:	caspase 3

Antibody:	anti-cleaved caspase-3
Detection system:	Secondary antibody coupled to Alexa Fluor 594

Results

4A +/+ ©

Specimen 4B upper +/+: embryonic day 10.75 (more

)
Note: Double labeled: red - Casp3; green - Lbx1 (assay MGI:6163816).

Structure	Level	Pattern	Image	Note
TS18: myotome	Present	Regionally restricted	4A +/+	Expressed in cells in the hypoglossal cord.

4B ki/ki upper ©

Specimen 4B upper ki/ki: embryonic day 10.75; Dpp9^tm1.1Npa/Dpp9^tm1.1Npa (more

)
Note: Double labeled: red - Casp3; green - Lbx1 (assay MGI:6163816).

Structure	Level	Pattern	Image	Note
TS18: myotome	Present	Regionally restricted	4B ki/ki upper	Increased expression in cells in the hypoglossal cord.

4B +/+ lower ©

Specimen 4B lower +/+: embryonic day 10.75 (more

)
Note: Double labeled: red - Casp3; green - Lbx1 (assay MGI:6163816).

Structure	Level	Pattern	Image	Note
TS18: 1st branchial arch	Present		4B +/+ lower

4B ki/ki lower ©

Specimen 4B lower ki/ki: embryonic day 10.75; Dpp9^tm1.1Npa/Dpp9^tm1.1Npa (more

)
Note: Double labeled: red - Casp3; green - Lbx1 (assay MGI:6163816).

Structure	Level	Pattern	Image	Note
TS18: 1st branchial arch	Present		4B ki/ki lower	Increased expression.

5A +/+ ©

Specimen 5A +/+: embryonic day 10.75 (more

)
Note: Double labeled: red - Casp3; green - Lbx1 (assay MGI:6163816).

Structure	Level	Pattern	Image	Note
TS18: forelimb bud	Present		5A +/+

5A ki/ki ©

Specimen 5A ki/ki: embryonic day 10.75; Dpp9^tm1.1Npa/Dpp9^tm1.1Npa (more

)
Note: Double labeled: red - Casp3; green - Lbx1 (assay MGI:6163816).

Structure	Level	Pattern	Image	Note
TS18: forelimb bud	Present		5A ki/ki	Comparable levels of expression compared with the wild-type.

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 03/25/2025 MGI 6.24