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Gene Expression Data
Assay Details
Assay
Reference: J:122606 Cheng LE, et al., The transcription factor Zfp423/OAZ is required for cerebellar development and CNS midline patterning. Dev Biol. 2007 Jul 1;307(1):43-52
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6162058
Gene symbol: Nefm
Gene name: neurofilament, medium polypeptide
Antibody: anti-Neurofilament M
Detection system: Biotinylated secondary antibody/[Strept]avidin coupled to horseradish peroxidase
Results
Specimen 6a: postnatal day 0 (more )
Structure Level Pattern Image Note
TS27: anterior commissure Present 6a
TS27: corpus callosum Present 6a
TS27: hippocampal commissure Present 6a
Specimen 6b: postnatal day 0; Zfp423tm1Reed/Zfp423tm1Reed (more )
Structure Level Pattern Image Note
TS27: anterior commissure Present Regionally restricted 6b Authors report defects in corpus callosum and hippocampal axons fail to cross midline, and swirl into Probst bundles.
TS27: corpus callosum Present Regionally restricted 6b Authors report defects in corpus callosum and hippocampal axons fail to cross midline, and swirl into Probst bundles.
TS27: hippocampal commissure Present Regionally restricted 6b Authors report defects in corpus callosum and hippocampal axons fail to cross midline, and swirl into Probst bundles.
Specimen 6c: postnatal day 0 (more )
Structure Level Pattern Image Note
TS27: telencephalon Present 6c
Specimen 6d: postnatal day 0; Zfp423tm1Reed/Zfp423tm1Reed (more )
Structure Level Pattern Image Note
TS27: telencephalon Present Regionally restricted 6d In some mutants, enlargement of cerebral ventricle is observed, along with shrinkage of the thalamus.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory