Gene Expression Data
Assay Details
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Assay
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Reference:
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J:121343
Lahteenmaki M, et al., Increased apoptosis of parasympathetic but not enteric neurons in mice lacking GFRalpha2. Dev Biol. 2007 May 1;305(1):325-32
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Assay type:
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Immunohistochemistry
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MGI Accession ID:
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MGI:6161689
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Gene symbol:
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Uchl1
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Gene name:
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ubiquitin carboxy-terminal hydrolase L1
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Antibody:
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anti-PGP9.5
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Detection system:
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Cy2
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Assay notes:
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Data presented in Figure 2. Two antibodies recognizing this gene were described. Antibody anti-PGP9.5 MGI:6161674 may have been used in this assay.
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Results
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Specimen
E15.5 WT:
embryonic day 15.5
(more  )
Specimen
E15.5 WT:
(close  )
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Genetic Background:
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involves: C57BL/6JOlaHsd
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Age:
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embryonic day 15.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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| Structure |
Level |
Pattern |
Image |
Note |
| TS23: pancreas |
Present |
Regionally restricted |
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Expression in neuronal cells.
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Specimen
E15.5 KO:
(close )
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Genetic Background:
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involves: 129S1/Sv * 129X1/SvJ * C57BL/6J
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Mutant Allele(s):
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Gfra2tm1Msa/Gfra2tm1Msa
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Age:
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embryonic day 15.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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| Structure |
Level |
Pattern |
Image |
Note |
| TS23: pancreas |
Present |
Regionally restricted |
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Authors report no significant difference in total number of expressing intrapancreatic cells in mutant compared to wild-type.
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Specimen
E16.5 WT:
embryonic day 16.5
(more )
Specimen
E16.5 WT:
(close )
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Genetic Background:
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involves: C57BL/6JOlaHsd
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Age:
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embryonic day 16.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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| Structure |
Level |
Pattern |
Image |
Note |
| TS24: pancreas |
Present |
Regionally restricted |
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Expression in neuronal cells.
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Specimen
E16.5 KO:
(close )
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Genetic Background:
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involves: 129S1/Sv * 129X1/SvJ * C57BL/6J
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Mutant Allele(s):
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Gfra2tm1Msa/Gfra2tm1Msa
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Age:
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embryonic day 16.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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| Structure |
Level |
Pattern |
Image |
Note |
| TS24: pancreas |
Present |
Regionally restricted |
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Authors report no significant difference in total number of expressing intrapancreatic cells in mutant compared to wild-type.
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Specimen
E17.5 WT:
embryonic day 17.5
(more )
Specimen
E17.5 WT:
(close )
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Genetic Background:
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involves: C57BL/6JOlaHsd
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Age:
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embryonic day 17.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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| Structure |
Level |
Pattern |
Image |
Note |
| TS25: pancreas |
Present |
Regionally restricted |
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Expression in neuronal cells.
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Specimen
E17.5 KO:
(close )
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Genetic Background:
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involves: 129S1/Sv * 129X1/SvJ * C57BL/6J
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Mutant Allele(s):
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Gfra2tm1Msa/Gfra2tm1Msa
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Age:
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embryonic day 17.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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| Structure |
Level |
Pattern |
Image |
Note |
| TS25: pancreas |
Weak |
Regionally restricted |
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Significantly lower number of expressing intrapancreatic cells in mutant compared to wild-type embryos.
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Specimen
P0.5 WT:
postnatal day 0.5
(more )
Specimen
P0.5 WT:
(close )
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Genetic Background:
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involves: C57BL/6JOlaHsd
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Age:
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postnatal day 0.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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| Structure |
Level |
Pattern |
Image |
Note |
| TS27: pancreas |
Present |
Regionally restricted |
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Expression in neuronal cells.
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Specimen
P0.5 KO:
(close )
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Genetic Background:
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involves: 129S1/Sv * 129X1/SvJ * C57BL/6J
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Mutant Allele(s):
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Gfra2tm1Msa/Gfra2tm1Msa
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Age:
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postnatal day 0.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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| Structure |
Level |
Pattern |
Image |
Note |
| TS27: pancreas |
Weak |
Regionally restricted |
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Authors report ~75% less expressing intrapancreatic cells than wild-type mice.
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Specimen
P4.5 WT:
postnatal day 4.5
(more )
Specimen
P4.5 WT:
(close )
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Genetic Background:
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involves: C57BL/6JOlaHsd
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Age:
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postnatal day 4.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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| Structure |
Level |
Pattern |
Image |
Note |
| TS28: pancreas |
Present |
Regionally restricted |
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Expression in neuronal cells.
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Specimen
P4.5 KO:
(close )
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Genetic Background:
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involves: 129S1/Sv * 129X1/SvJ * C57BL/6J
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Mutant Allele(s):
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Gfra2tm1Msa/Gfra2tm1Msa
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Age:
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postnatal day 4.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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| Structure |
Level |
Pattern |
Image |
Note |
| TS28: pancreas |
Weak |
Regionally restricted |
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Authors report ~85% loss of intrapancreatic neurons from P4 onwards.
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Specimen
adult WT:
postnatal adult
(more )
Specimen
adult WT:
(close )
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Genetic Background:
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involves: C57BL/6JOlaHsd
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Age:
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postnatal adult
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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| Structure |
Level |
Pattern |
Image |
Note |
| TS28: pancreas |
Present |
Regionally restricted |
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Expression in neuronal cells.
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Specimen
adult KO:
(close )
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Genetic Background:
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involves: 129S1/Sv * 129X1/SvJ * C57BL/6J
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Mutant Allele(s):
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Gfra2tm1Msa/Gfra2tm1Msa
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Age:
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postnatal adult
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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| Structure |
Level |
Pattern |
Image |
Note |
| TS28: pancreas |
Weak |
Regionally restricted |
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Authors report ~85% loss of intrapancreatic neurons from P4 onwards.
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Analysis Tools