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Gene Expression Data
Assay Details
Assay
Reference: J:253679 Hirst CS, et al., Kif1bp loss in mice leads to defects in the peripheral and central nervous system and perinatal death. Sci Rep. 2017 Nov 30;7(1):16676
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6160911
Gene symbol: Phox2b
Gene name: paired-like homeobox 2b
Antibody: Anti-Phox2b
Detection system: Secondary antibody coupled to fluorescein
Assay notes: This publication created two Kif1bp mutant lines. Either MGI:6154375 or MGI:3154376 was used for this assay.
Results
Specimen 8 Kif1bp+/+: postnatal day 0 (more )
Note: Triple labeled: green - Phox2b; red - Chat (assay MGI:6160910); blue - Tacr1 (assay MGI:6160912).
Structure Level Pattern Image Note
TS27: brainstem nucleus Present 8_merge top , 8_Phox2b top The retrotrapezoid nucleus/parafacial respiratory group was revealed by immunostaining.
Specimen 8 Kif1bp-/-: postnatal day 0; Kifbpem1Hmy/Kifbpem1Hmy (more )
Note: Triple labeled: green - Phox2b; red - Chat (assay MGI:6160910); blue - Tacr1 (assay MGI:6160912).
Structure Level Pattern Image Note
TS27: brainstem nucleus Present 8_Phox2b bottom , 8_merge bottom The retrotrapezoid nucleus/parafacial respiratory group was revealed by immunostaining. There was no noticeable difference between mutant and wild type.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/18/2025
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