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Gene Expression Data
Assay Details
Assay
Reference: J:118798 Fan B, et al., Hepatocyte growth factor activator inhibitor-1 (HAI-1) is essential for the integrity of basement membranes in the developing placental labyrinth. Dev Biol. 2007 Mar 1;303(1):222-30
Assay type: RNA in situ
MGI Accession ID: MGI:6158921
Gene symbol: Gcm1
Gene name: glial cells missing homolog 1
Probe: Gcm1 probe3
Probe preparation: Antisense labelled with digoxigenin RNA
Results
Specimen 2B +/+ (upper): embryonic day 9.5 (more )
Structure Level Pattern Image Note
TS15: labyrinthine zone Present Widespread 2B +/+ (upper) Broad expression throughout labyrinth.
Specimen 2B +/+ (lower): embryonic day 9.5 (more )
Structure Level Pattern Image Note
TS15: chorionic plate Present Regionally restricted 2B +/+ (lower) Intensified expression at evagination points at chorioallantoic plate.
TS15: trophoblast giant cell Strong Regionally restricted 2B +/+ (lower) Strong expression in elongated trophoblast cells at branching sites.
Specimen 2B -/- (upper): embryonic day 9.5; Spint1Gt(OST380474)Lex/Spint1Gt(OST380474)Lex (more )
Structure Level Pattern Image Note
TS15: labyrinthine zone Present Widespread 2B -/- (upper) Authors report a similar expression pattern to the of the wild-type placenta.
Specimen 2B -/- (lower): embryonic day 9.5; Spint1Gt(OST380474)Lex/Spint1Gt(OST380474)Lex (more )
Structure Level Pattern Image Note
TS15: trophoblast giant cell Present Regionally restricted 2B -/- (lower) Authors state most initial branching sites fail to expand and to develop a villous morphology.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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05/28/2024
MGI 6.13 		The Jackson Laboratory