Gene Expression Data
Assay Details
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Assay
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Reference:
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J:109335
Withington SL, et al., Loss of Cited2 affects trophoblast formation and vascularization of the mouse placenta. Dev Biol. 2006 Jun 1;294(1):67-82
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Assay type:
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Immunohistochemistry
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MGI Accession ID:
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MGI:6157482
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Gene symbol:
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Acta2
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Gene name:
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actin alpha 2, smooth muscle, aorta
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Results
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Specimen
7D:
embryonic day 11.5
(more  )
Specimen
7D:
(close  )
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Genetic Background:
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involves: C57BL/6
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Age:
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embryonic day 11.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Paraffin
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| Structure |
Level |
Pattern |
Image |
Note |
| TS19: labyrinthine zone |
Strong |
Regionally restricted |
7D
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Strong expression in multiple densely packed layers of the large blood fetal vessels at base of labyrinth.
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Specimen
7E:
embryonic day 11.5
(more )
Specimen
7E:
(close )
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Genetic Background:
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involves: C57BL/6
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Age:
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embryonic day 11.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Paraffin
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| Structure |
Level |
Pattern |
Image |
Note |
| TS19: labyrinthine zone |
Present |
Regionally restricted |
7E
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Expression in smaller fetal blood vessels as they branched and penetrated throughout labyrinth, right up to the border with the spongiotrophoblast layer.
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Specimen
7F:
embryonic day 11.5
(more )
Specimen
7F:
(close )
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Genetic Background:
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involves: C57BL/6
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Age:
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embryonic day 11.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Paraffin
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| Structure |
Level |
Pattern |
Image |
Note |
| TS19: labyrinthine zone |
Present |
Regionally restricted |
7F
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Expression in smaller fetal blood vessels scattered fairly evenly throughout the labyrinth. No expression associated with maternal blood spaces in the labyrinth
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Specimen
7G:
(close )
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Genetic Background:
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involves: 129P2/OlaHsd * C57BL/6
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Mutant Allele(s):
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Cited2tm1Jpmb/Cited2tm1Jpmb
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Age:
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embryonic day 11.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Paraffin
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| Structure |
Level |
Pattern |
Image |
Note |
| TS19: labyrinthine zone |
Weak |
Regionally restricted |
7G
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Expression in wall of large fetal blood vessels at base of labyrinth. Authors report density of expressing cells was clearly reduced and cells were less well organlized.
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Specimen
7H:
(close )
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Genetic Background:
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involves: 129P2/OlaHsd * C57BL/6
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Mutant Allele(s):
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Cited2tm1Jpmb/Cited2tm1Jpmb
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Age:
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embryonic day 11.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Paraffin
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| Structure |
Level |
Pattern |
Image |
Note |
| TS19: labyrinthine zone |
Weak |
Regionally restricted |
7H
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Expression in smaller blood vessels traversing throughout labyrinth. Authors report densitiy of expressing cells was also greatly reduced.
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Specimen
7I:
(close )
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Genetic Background:
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involves: 129P2/OlaHsd * C57BL/6
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Mutant Allele(s):
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Cited2tm1Jpmb/Cited2tm1Jpmb
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Age:
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embryonic day 11.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Paraffin
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| Structure |
Level |
Pattern |
Image |
Note |
| TS19: labyrinthine zone |
Weak |
Regionally restricted |
7I
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Expressing scattered clumps of cells throughout the labyrinth. Authors reprot the overall number of clumps was reduced, indicating reduced density of fetal blood vessels.
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Analysis Tools