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Gene Expression Data
Assay Details
Assay
Reference: J:207829 Dupuis LE, et al., Small leucine-rich proteoglycans exhibit unique spatiotemporal expression profiles during cardiac valve development. Dev Dyn. 2014 Apr;243(4):601-11
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6154360
Gene symbol: Dcn
Gene name: decorin
Antibody: Decorin antibody (AF1060)
Detection system: Secondary antibody
Results
Specimen 1B: embryonic day 10.5 (more )
Note: Double labeled: green - Dcn; blue - Actc1 (assay MGI:6154957). Amsterdam fixative.
Structure Level Pattern Image Note
TS17: trunk Present Regionally restricted 1B Expression is in non-cardiovascular tissues.
TS17: heart Absent 1B
Specimen 1B': embryonic day 10.5 (more )
Note: Double labeled: green - Dcn; blue - Actc1 (assay MGI:6154957). Amsterdam fixative.
Structure Level Pattern Image Note
TS17: heart Absent 1B'
TS17: outflow tract Absent 1B'
Specimen 1B'': embryonic day 10.5 (more )
Note: Double labeled: green - Dcn; blue - Actc1 (assay MGI:6154957). Amsterdam fixative.
Structure Level Pattern Image Note
TS17: atrioventricular endocardial cushion Absent 1B''
TS17: heart Absent 1B''
Specimen 2G: embryonic day 14.5 (more )
Note: Double labeled: green - Dcn; blue - Actc1 (assay MGI:6154957). Amsterdam fixative.
Structure Level Pattern Image Note
TS22: cardiac muscle tissue Present Regionally restricted 2G Expression is within the cusp commissures, the area where the valve mesenchyme and myocardium meet.
TS22: heart valve Present Regionally restricted 2G Expression is within the cusp commissures, the area where the valve mesenchyme and myocardium meet.
TS22: pulmonary artery Present Regionally restricted 2G Expression is in the adventitial layer of the wall of the aorta.
TS22: great vessel of heart Present Regionally restricted 2G Expression is in the adventitial layer of the wall of the aorta.
Specimen 2H: embryonic day 14.5 (more )
Note: Double labeled: green - Dcn; blue - Actc1 (assay MGI:6154957).
Structure Level Pattern Image Note
TS22: pulmonary artery Present Regionally restricted 2H Expression is in the adventitial layer of the wall of the aorta.
Specimen 2I: embryonic day 14.5 (more )
Note: Double labeled: green - Dcn; blue - Actc1 (assay MGI:6154957).
Structure Level Pattern Image Note
TS22: cardiac muscle tissue Present Regionally restricted 2I Expression is within the cusp commissures, the area where the valve mesenchyme and myocardium meet.
TS22: heart valve Present Regionally restricted 2I Expression is within the cusp commissures, the area where the valve mesenchyme and myocardium meet.
Specimen 2J: embryonic day 14.5 (more )
Note: Double labeled: green - Dcn; blue - Actc1 (assay MGI:6154957). Amsterdam fixative.
Structure Level Pattern Image Note
TS22: cardiac muscle tissue Present Regionally restricted 2J Expression is within the cusp commissures, the area where the valve mesenchyme and myocardium meet.
TS22: heart valve Present Regionally restricted 2J Expression is within the cusp commissures, the area where the valve mesenchyme and myocardium meet.
Specimen 2K: embryonic day 14.5 (more )
Note: Double labeled: green - Dcn; blue - Actc1 (assay MGI:6154957). Amsterdam fixative.
Structure Level Pattern Image Note
TS22: great vessel of heart Present 2K Expression is in the adventitial layer of the wall of the aorta.
Specimen 2L: embryonic day 14.5 (more )
Note: Double labeled: green - Dcn; blue - Actc1 (assay MGI:6154957). Amsterdam fixative.
Structure Level Pattern Image Note
TS22: mitral valve Absent 2L
Specimen 3F: postnatal day 0 (more )
Note: Double labeled: green - Dcn; blue - Actc1 (assay MGI:6154957). Amsterdam fixative.
Structure Level Pattern Image Note
TS27: aortic valve Present Regionally restricted 3F , 3F' Expression is in the cusps.
TS27: mitral valve Present Regionally restricted 3F , 3F' Expression is in the cusps.
TS27: pulmonary valve Present Regionally restricted 3F , 3F' Expression is in the cusps.
Specimen 3G: postnatal day 0 (more )
Note: Double labeled: green - Dcn; blue - Actc1 (assay MGI:6154957).
Structure Level Pattern Image Note
TS27: pulmonary valve Present Regionally restricted 3G Expression is in the cusps.
Specimen 3H: postnatal day 0 (more )
Note: Double labeled: green - Dcn; blue - Actc1 (assay MGI:6154957). Amsterdam fixative.
Structure Level Pattern Image Note
TS27: aorta tunica adventitia Very strong 3H
TS27: left ventricle cardiac muscle Present Regionally restricted 3H Expression is at the myocardial attachment regions of the cusps.
Specimen 3I: postnatal day 0 (more )
Note: Double labeled: green - Dcn; blue - Actc1 (assay MGI:6154957). Amsterdam fixative.
Structure Level Pattern Image Note
TS27: mitral valve Present Regionally restricted 3I Expression is in areas where the leaflets anchor into the myocardium.
Specimen 3J: postnatal day 0 (more )
Note: Double labeled: green - Dcn; blue - Actc1 (assay MGI:6154957). Amsterdam fixative.
Structure Level Pattern Image Note
TS27: pericardium Present Regionally restricted 3J Expression is in the extra-cellular matrix.
Specimen 4E: postnatal month 1 (more )
Note: Double labeled: green - Dcn; blue - Actc1 (assay MGI:6154957). Amsterdam fixative.
Structure Level Pattern Image Note
TS28: aortic valve Very strong Regionally restricted 4E Expression is in regions where the cusp hinges anchor to surrounding tissues.
TS28: pulmonary valve Very strong Regionally restricted 4E Expression is in regions where the cusp hinges anchor to surrounding tissues and is in the cusps.
TS28: pulmonary valve anulus Present 4E
Specimen 4F: postnatal month 1 (more )
Note: Double labeled: green - Dcn; blue - Actc1 (assay MGI:6154957). Amsterdam fixative.
Structure Level Pattern Image Note
TS28: aortic valve Very strong Regionally restricted 4F' , 4F Expression is in regions where the cusp hinges anchor to surrounding tissues and in the cusp hinge.
TS28: aorta tunica adventitia Very strong 4F , 4F''
Specimen 4G: postnatal month 1 (more )
Note: Double labeled: green - Dcn; blue - Actc1 (assay MGI:6154957).
Structure Level Pattern Image Note
TS28: aortic valve Strong Regionally restricted 4G Expression is in the distal cusps.
Specimen 4H: postnatal month 1 (more )
Note: Double labeled: green - Dcn; blue - Actc1 (assay MGI:6154957). Amsterdam fixative.
Structure Level Pattern Image Note
TS28: mitral valve Present 4H Expression is strong in fibrous attachment of the posterior leaflet.
TS28: chordae tendinae Present 4H
Specimen 5D: postnatal adult (more )
Note: Double labeled: green - Dcn; blue - Actc1 (assay MGI:6154957). Amsterdam fixative.
Structure Level Pattern Image Note
TS28: semilunar valve Present 5D
TS28: pulmonary artery Strong Regionally restricted 5D Expression is in the adventitia.
Specimen 5E: postnatal adult (more )
Note: Double labeled: green - Dcn; blue - Actc1 (assay MGI:6154957). Amsterdam fixative.
Structure Level Pattern Image Note
TS28: semilunar valve Present 5E' , 5E
TS28: aorta Strong 5E' , 5E
TS28: pulmonary artery Strong Regionally restricted 5E , 5E' Expression is in the adventitia.
Specimen 5F: postnatal adult (more )
Note: Double labeled: green - Dcn; blue - Actc1 (assay MGI:6154957). Amsterdam fixative.
Structure Level Pattern Image Note
TS28: mitral valve Strong Regionally restricted 5F' , 5F Expression is withing the atrial layer.
Specimen not shown: postnatal day 0 (more )
Note: Also stained for Actc1 (assay MGI:6154957). Amsterdam fixative.
Structure Level Pattern Image Note
TS27: tricuspid valve leaflet Present Regionally restricted Expression is in the cups.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory