Gene Expression Data
Assay Details
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Assay
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Reference:
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J:100569
Sajithlal G, et al., Eya 1 acts as a critical regulator for specifying the metanephric mesenchyme. Dev Biol. 2005 Aug 15;284(2):323-36
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Assay type:
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RNA in situ
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MGI Accession ID:
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MGI:6153571
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Gene symbol:
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Ret
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Gene name:
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ret proto-oncogene
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Results
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Specimen
3A:
embryonic day 10.5
(more  )
Specimen
3A:
(close  )
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Genetic Background:
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Not Specified
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Age:
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embryonic day 10.5
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Sex:
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Not Specified
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Type:
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whole mount
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Fixation:
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4% Paraformaldehyde
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| Structure |
Level |
Pattern |
Image |
Note |
| TS17: nephric duct |
Strong |
Regionally restricted |
3A
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Strong expression in ureteric bud emerging from caudal Wolffian duct.
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Specimen
3B:
(close )
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Genetic Background:
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involves: 129S1/Sv * 129X1/SvJ
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Mutant Allele(s):
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Eya1tm1Rilm/Eya1tm1Rilm
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Age:
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embryonic day 10.5
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Sex:
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Not Specified
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Type:
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whole mount
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Fixation:
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4% Paraformaldehyde
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| Structure |
Level |
Pattern |
Image |
Note |
| TS17: nephric duct |
Present |
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3B
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Expression in Wolffian duct - not induced for ureteric bud formation.
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Specimen
3C:
embryonic day 11.0
(more )
Specimen
3C:
(close )
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Genetic Background:
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Not Specified
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Age:
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embryonic day 11.0
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Sex:
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Not Specified
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Type:
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whole mount
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Fixation:
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4% Paraformaldehyde
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| Structure |
Level |
Pattern |
Image |
Note |
| TS18: ureteric bud |
Strong |
Regionally restricted |
3C
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Strong expression in ureteric bud elongating to invade mesenchyme.
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Specimen
3D:
(close )
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Genetic Background:
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involves: 129S1/Sv * 129X1/SvJ
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Mutant Allele(s):
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Eya1tm1Rilm/Eya1tm1Rilm
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Age:
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embryonic day 11.0
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Sex:
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Not Specified
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Type:
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whole mount
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Fixation:
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4% Paraformaldehyde
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| Structure |
Level |
Pattern |
Image |
Note |
| TS18: nephric duct |
Present |
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3D
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Expression in Wolffian duct - not induced for ureteric bud formation.
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Specimen
3E:
embryonic day 11.5
(more )
Specimen
3E:
(close )
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Genetic Background:
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Not Specified
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Age:
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embryonic day 11.5
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Sex:
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Not Specified
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Type:
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whole mount
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Fixation:
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4% Paraformaldehyde
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| Structure |
Level |
Pattern |
Image |
Note |
| TS19: ureteric bud |
Strong |
Regionally restricted |
3E
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Strong expression in ureteric bud undergoing branching morphogenesis to form first T-shaped bud.
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Specimen
3F:
(close )
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Genetic Background:
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involves: 129S1/Sv * 129X1/SvJ
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Mutant Allele(s):
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Eya1tm1Rilm/Eya1tm1Rilm
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Age:
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embryonic day 11.5
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Sex:
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Not Specified
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Type:
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whole mount
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Fixation:
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4% Paraformaldehyde
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| Structure |
Level |
Pattern |
Image |
Note |
| TS19: nephric duct |
Present |
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3F
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Expression in Wolffian duct - not induced for ureteric bud formation.
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Specimen
4E:
embryonic day 11.25
(more )
Specimen
4E:
(close )
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Genetic Background:
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Not Specified
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Age:
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embryonic day 11.25
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Sex:
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Not Specified
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Type:
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whole mount
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Fixation:
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4% Paraformaldehyde
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| Structure |
Level |
Pattern |
Image |
Note |
| TS19: ureteric bud |
Present |
Regionally restricted |
4E
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Authors report normal ureteric bud invasion into mesenchyme and induced branching mesenchyme.
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| TS19: ureteric tip |
Strong |
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4E
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HIgher level of expression at tip of bud.
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Specimen
4F:
(close )
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Genetic Background:
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involves: 129S1/Sv * 129X1/SvJ * C3HeB/FeJ
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Mutant Allele(s):
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Eya1bor/Eya1tm1Rilm
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Age:
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embryonic day 11.25
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Sex:
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Not Specified
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Type:
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whole mount
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Fixation:
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4% Paraformaldehyde
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| Structure |
Level |
Pattern |
Image |
Note |
| TS19: ureteric bud |
Present |
Regionally restricted |
4F
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Authors report normal ureteric bud outgrowth but distrupted branching morphogenesis.
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| TS19: ureteric tip |
Weak |
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4F
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Reduced expression at tip of bud.
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Specimen
6G:
(close )
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Genetic Background:
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involves: 129S1/Sv * 129X1/SvJ
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Mutant Allele(s):
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Pax2tm1Pgr/Pax2tm1Pgr
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Age:
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embryonic day 10.5
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Sex:
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Not Specified
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Type:
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whole mount
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Fixation:
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4% Paraformaldehyde
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| Structure |
Level |
Pattern |
Image |
Note |
| TS17: nephric duct |
Present |
Regionally restricted |
6G
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Authors report ureteric bud formation at E10.5
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Specimen
6H:
(close )
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Genetic Background:
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involves: 129
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Mutant Allele(s):
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Eya1tm1Rilm/Eya1+
Pax2tm1Pgr/Pax2+
Six1tm1Mair/Six1+
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Age:
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embryonic day 10.5
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Sex:
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Not Specified
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Type:
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whole mount
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Fixation:
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4% Paraformaldehyde
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| Structure |
Level |
Pattern |
Image |
Note |
| TS17: nephric duct |
Present |
Regionally restricted |
6H
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Authors report normal ureteric bud formation at E10.5.
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Specimen
6I:
(close )
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Genetic Background:
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involves: 129S1/Sv * 129X1/SvJ
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Mutant Allele(s):
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Pax2tm1Pgr/Pax2tm1Pgr
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Age:
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embryonic day 11.5
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Sex:
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Not Specified
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Type:
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whole mount
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Fixation:
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4% Paraformaldehyde
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| Structure |
Level |
Pattern |
Image |
Note |
| TS19: ureteric bud |
Present |
Regionally restricted |
6I
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Authors report ureteric bud branching at E11.5.
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Specimen
6J:
(close )
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Genetic Background:
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involves: 129
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Mutant Allele(s):
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Eya1tm1Rilm/Eya1+
Pax2tm1Pgr/Pax2+
Six1tm1Mair/Six1+
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Age:
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embryonic day 11.5
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Sex:
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Not Specified
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Type:
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whole mount
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Fixation:
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4% Paraformaldehyde
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| Structure |
Level |
Pattern |
Image |
Note |
| TS19: ureteric bud |
Present |
Regionally restricted |
6J
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Authors report failure of ureteric bud to branch out.
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Analysis Tools