Gli1 RNA in situ Gene Expression Assay

Gene Expression Data
Assay Details

Assay

Reference:	J:121609 Wang C, et al., The Shh-independent activator function of the full-length Gli3 protein and its role in vertebrate limb digit patterning. Dev Biol. 2007 May 15;305(2):460-9
Assay type:	RNA in situ
MGI Accession ID:	MGI:6149481
Gene symbol:	Gli1
Gene name:	GLI-Kruppel family member GLI1

Probe:

Gli1 probe30

Results

6A ©

Specimen 6A: embryonic day 10.5 (more

)

Structure	Level	Pattern	Image	Note
TS17: forelimb bud	Present		6A

6B ©

Specimen 6B: embryonic day 10.5; Gli3^tm2Blnw/Gli3^tm2Blnw (more

)

Structure	Level	Pattern	Image	Note
TS17: forelimb bud	Present	Regionally restricted	6B	Ectopic expression in anterior region of limb bud slightly higher than in Gli3-/- limb buds.

6C ©

Specimen 6C: embryonic day 10.5; Gli3^tm2Blnw/Gli3^Xt (more

)

Structure	Level	Pattern	Image	Note
TS17: forelimb bud	Present	Regionally restricted	6C	Ectopic expression in anterior region of limb bud slightly higher than in Gli3-/- limb buds.

6D ©

Specimen 6D: embryonic day 10.5; Gli3^Xt/Gli3^Xt (more

)

Structure	Level	Pattern	Image	Note
TS17: forelimb bud	Present	Regionally restricted	6D	Authors report ectopic expression in anterior region of limb bud.

6E ©

Specimen 6E: embryonic day 10.5; Gli3^tm1Urt/Gli3^tm2Blnw (more

)

Structure	Level	Pattern	Image	Note
TS17: forelimb bud	Present		6E	Authors state that ectopic expression was suppressed.

7A ©

Specimen 7A: embryonic day 10.5 (more

)

Structure	Level	Pattern	Image	Note
TS17: forelimb bud	Present		7A

7B ©

Specimen 7B: embryonic day 10.5; Shh^tm1Chg/Shh^tm1Chg (more

)

Structure	Level	Pattern	Image	Note
TS17: forelimb bud	Absent		7B

7C ©

Specimen 7C: embryonic day 10.5; Gli3^tm2Blnw/Gli3^tm2Blnw, Shh^tm1Chg/Shh⁺ (more

)

Structure	Level	Pattern	Image	Note
TS17: forelimb bud	Strong	Widespread	7C	Expression upregulated and expanded throughout limb buds.

7D ©

Specimen 7D: embryonic day 10.5; Gli3^tm2Blnw/Gli3^tm2Blnw, Shh^tm1Chg/Shh^tm1Chg (more

)

Structure	Level	Pattern	Image	Note
TS17: forelimb bud	Strong		7D	Expression upregulated and expanded throughout limb buds.

7E ©

Specimen 7E: embryonic day 10.5; Gli3^tm2Blnw/Gli3⁺, Shh^tm1Chg/Shh^tm1Chg (more

)

Structure	Level	Pattern	Image	Note
TS17: forelimb bud	Present	Regionally restricted	7E	Anterior expression suppressed to a very low level.

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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