About   Help   FAQ
Gene Expression Data
Assay Details
Assay
Reference: J:134595 Anthony TE, et al., The folate metabolic enzyme ALDH1L1 is restricted to the midline of the early CNS, suggesting a role in human neural tube defects. J Comp Neurol. 2007 Jan 10;500(2):368-83
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6149222
Gene symbol: Mthfd1
Gene name: methylenetetrahydrofolate dehydrogenase (NADP+ dependent), methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthase
Antibody: anti-MTHFD1
Detection system: Secondary antibody
Results
Specimen 2A: embryonic day 8.5 (more )
Structure Level Pattern Image Note
TS13: neural tube Present Ubiquitous 2A
Specimen 2B: embryonic day 9.5 (more )
Structure Level Pattern Image Note
TS15: neural tube Present Ubiquitous 2B
Specimen 2C: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: spinal cord Present 2C Expression is in both neurons and radial glia.
Specimen 2D: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: spinal cord Present 2D Expression is in both neurons and radial glia.
Specimen 2E: embryonic day 12.5 (more )
Note: Double labeled: red - Mthfd1; green - Tubb3 (assay MGI:6149223).
Structure Level Pattern Image Note
TS20: spinal cord Present 2G , 2E Expression is in both neurons and radial glia.
Specimen 2H: embryonic day 12.5 (more )
Note: Double labeled: red - Mthfd1; green - Nes (assay MGI:6149221).
Structure Level Pattern Image Note
TS20: spinal cord Present 2J , 2H
Specimen 2K: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: neocortex Present 2K
Specimen 2L: embryonic day 12.5 (more )
Note: Double labeled: red - Mthfd1; green - Tubb3 (assay MGI:6149223).
Structure Level Pattern Image Note
TS20: neocortex Present 2L , 2N
Specimen 2P: embryonic day 17.5 (more )
Structure Level Pattern Image Note
TS25: cerebral cortex Present 2P Expression is in neuronal and radial glial cell bodies.
Specimen 2R: embryonic day 17.5 (more )
Structure Level Pattern Image Note
TS25: cerebral cortex Present 2R Expression is in neuronal and radial glial cell bodies.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
05/07/2024
MGI 6.23 		The Jackson Laboratory