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Gene Expression Data
Assay Details
Assay
Reference: J:116479 Luxardi G, et al., Glypicans are differentially expressed during patterning and neurogenesis of early mouse brain. Biochem Biophys Res Commun. 2007 Jan 5;352(1):55-60
Assay type: RNA in situ
MGI Accession ID: MGI:6148305
Gene symbol: Gpc4
Gene name: glypican 4
Probe: Gpc-4 cDNA1
Probe preparation: Antisense labelled with digoxigenin RNA
Results
Specimen 1A Early streak: embryonic day 6.5 (more )
Structure Level Pattern Image Note
TS9: anterior visceral endoderm Present 1A E6.5
Specimen 1A Mid streak: embryonic day 6.7 (more )
Structure Level Pattern Image Note
TS10: anterior visceral endoderm Present 1A E6.7
Specimen 1A Late streak-early bud: embryonic day 7.25 (more )
Structure Level Pattern Image Note
TS10: anterior visceral endoderm Present 1A E7.25
Specimen 1B Early streak WT: embryonic day 6.5 (more )
Structure Level Pattern Image Note
TS9: anterior visceral endoderm Present 1B WT whole mount
Specimen 1B Early streak Otx2-/-: embryonic day 6.5; Otx2tm1Sla/Otx2tm1Sla (more )
Structure Level Pattern Image Note
TS9: posterior visceral endoderm Present Regionally restricted 1B Otx2-/- whole mount Expression was detected in distal visceral endoderm.
Specimen 1B Early streak WT: embryonic day 6.5 (more )
Note: Embedded in methacrylate.
Structure Level Pattern Image Note
TS9: anterior visceral endoderm Present 1B WT section
Specimen 1B Early streak Otx2-/-: embryonic day 6.5; Otx2tm1Sla/Otx2tm1Sla (more )
Note: Embedded in methacrylate.
Structure Level Pattern Image Note
TS9: posterior visceral endoderm Present Regionally restricted 1B Otx2-/- section Expression was detected in distal visceral endoderm.
Specimen 2A: embryonic day 7.5 (more )
Structure Level Pattern Image Note
TS11: embryo Present Regionally restricted 2A gpc-4 Expression was restricted to the developing anterior structures and posteriorly from the node.
Specimen 2B top: embryonic day 8.5 (more )
Note: 7 somites.
Structure Level Pattern Image Note
TS13: future prosencephalon Present Regionally restricted 2B gpc-4 top Expression was detected in the forebrain. This expression domain encompasses the anterior neural ridge.
TS13: primitive streak Present 2B gpc-4 top
Specimen 2B bottom: embryonic day 8.5 (more )
Note: 7 somites.
Structure Level Pattern Image Note
TS13: future prosencephalon Present Regionally restricted 2B gpc-4 bottom Expression was detected in the forebrain. This expression domain encompasses the anterior neural ridge.
Specimen 2B bottom inset: embryonic day 8.5 (more )
Note: 7 somites.
Structure Level Pattern Image Note
TS13: future prosencephalon Present Regionally restricted 2B gpc-4 inset Expression was detected in the forebrain. This expression domain encompasses the anterior neural ridge.
Specimen 3 top: embryonic day 9.5 (more )
Structure Level Pattern Image Note
TS15: telencephalon Present Regionally restricted 3_gpc-4 top Expression was abundant in dorsal and ventral neuroepithelium in the telencephalon.
TS15: future midbrain Present 3_gpc-4 top
TS15: limb Present 3_gpc-4 top
TS15: somite Present 3_gpc-4 top
TS15: tail Present 3_gpc-4 top
TS15: 1st branchial arch Present Regionally restricted 3_gpc-4 top Expression was detected in the proximal region.
TS15: 2nd branchial arch Present Regionally restricted 3_gpc-4 top Expression was detected in the proximal region.
Specimen 3 top insert: embryonic day 9.5 (more )
Structure Level Pattern Image Note
TS15: neural ectoderm Present 3_gpc-4 inset top
Specimen 3 bottom: embryonic day 9.5 (more )
Structure Level Pattern Image Note
TS15: telencephalon Present Regionally restricted 3_gpc-4 bottom Expression was abundant in dorsal and ventral neuroepithelium in the telencephalon.
TS15: 1st branchial arch Present Regionally restricted 3_gpc-4 bottom Expression was detected in the proximal region.
TS15: heart Present 3_gpc-4 bottom
Specimen 3 bottom insert: embryonic day 9.5 (more )
Structure Level Pattern Image Note
TS15: future forebrain Present 3_gpc-4 inset bottom
TS15: non-neural ectoderm Present Regionally restricted 3_gpc-4 inset bottom Expression in ectodermal tissue adjacent to the neural ectoderm.
Specimen 4 top: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: 1st branchial arch Present 4_gpc-4 top
TS17: 1st branchial arch mandibular component Present 4_gpc-4 top
TS17: 1st branchial arch maxillary component Present 4_gpc-4 top
TS17: 2nd branchial arch Present 4_gpc-4 top
TS17: limb Present 4_gpc-4 top
TS17: midbrain Present 4_gpc-4 top
TS17: somite Present 4_gpc-4 top
TS17: telencephalon Present 4_gpc-4 top
Specimen 4 middle: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: midbrain Present 4_gpc-4 middle
TS17: telencephalon Present 4_gpc-4 middle
Specimen 4 bottom: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: diencephalon Present Regionally restricted 4_gpc-4 bottom Expression was detected in the hypothalamus and adjacent to the optic stalk.
Specimen S1A: embryonic day 8.5 (more )
Note: 7 somites.
Structure Level Pattern Image Note
TS13: future brain neural fold Present Regionally restricted S1A Expression in the head region was restricted to the anterior neural fold. There was staining in the anterior neural ridge and the underlying neuroepithelium.
Specimen S1E: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: brain Present Regionally restricted S1E Expression was detected in the neuroepithelium of the lateral ventricle.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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01/28/2026
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