Isl1 Immunohistochemistry Gene Expression Assay

Gene Expression Data
Assay Details

Assay

Reference:	J:19896 Weinstein DC, et al., The winged-helix transcription factor HNF-3 beta is required for notochord development in the mouse embryo. Cell. 1994 Aug 26;78(4):575-88
Assay type:	Immunohistochemistry
MGI Accession ID:	MGI:6143853
Gene symbol:	Isl1
Gene name:	ISL1 transcription factor, LIM/homeodomain

Antibody:	anti-C-Isl-1 protein (K5)
Detection system:	Secondary antibody coupled to horseradish peroxidase

Results

Specimen 6C: embryonic day 9.5; Foxa2^tm1Dnl/Foxa2⁺ (more

)

Structure	Level	Pattern	Image	Note
TS15: neural tube lateral wall	Present	Regionally restricted	6C	Expressed in the nuclei of developing motor neurons in the ventral spinal cord adjacent to the floor plate.

Specimen 6D: embryonic day 9.5; Foxa2^tm1Dnl/Foxa2^tm1Dnl (more

)

Structure	Level	Pattern	Image	Note
TS15: neural tube	Absent		6D

Specimen not shown: embryonic day 9.5; Foxa2^tm1Dnl/Foxa2⁺ (more

)

Structure	Level	Pattern	Image	Note
TS15: dorsal root ganglion	Present
TS15: embryo mesoderm	Present

Specimen not shown: embryonic day 9.5; Foxa2^tm1Dnl/Foxa2^tm1Dnl (more

)

Structure	Level	Pattern	Image	Note
TS15: embryo mesoderm	Present	Regionally restricted		Expressed in the lateral mesenchyme.

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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