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Gene Expression Data
Assay Details
Assay
Reference: J:251844 Zamboni V, et al., Disruption of ArhGAP15 results in hyperactive Rac1, affects the architecture and function of hippocampal inhibitory neurons and causes cognitive deficits. Sci Rep. 2016 Oct 7;6:34877
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6115356
Gene symbol: Slc32a1
Gene name: solute carrier family 32 (GABA vesicular transporter), member 1
Antibody: anti-VGAT
Detection system: Secondary antibody coupled to Alexa Fluor 568
Results
Specimen 4c Wild-type: postnatal day 30 (more )
Structure Level Pattern Image Note
TS28: CA1 pyramidal cell layer Present Regionally restricted 4c Wild-type Expression in punctae on perisomatic surface of pyramidal neurons.
TS28: CA2 pyramidal cell layer Present Regionally restricted 4c Wild-type Expression in punctae on perisomatic surface of pyramidal neurons.
TS28: CA3 pyramidal cell layer Present Regionally restricted 4c Wild-type Expression in punctae on perisomatic surface of pyramidal neurons.

Specimen 4c ArhGAP45-/-: postnatal day 30; Arhgap15tm1Ehi/Arhgap15tm1Ehi (more )
Structure Level Pattern Image Note
TS28: CA1 pyramidal cell layer Weak Regionally restricted 4c ArhGAP15-/- Authors report significant reduction of expressing punctae in all regions of hippocampus compared with wild-type.
TS28: CA2 pyramidal cell layer Weak Regionally restricted 4c ArhGAP15-/- Authors report significant reduction of expressing punctae in all regions of hippocampus compared with wild-type.
TS28: CA3 pyramidal cell layer Weak Regionally restricted 4c ArhGAP15-/- Authors report significant reduction of expressing punctae in all regions of hippocampus compared with wild-type.

Specimen 4d Wild-type: postnatal day 30 (more )
Structure Level Pattern Image Note
TS28: dentate gyrus granule cell layer Present Regionally restricted 4d Wild-type

Specimen 4d ArhGAP15-/-: postnatal day 30; Arhgap15tm1Ehi/Arhgap15tm1Ehi (more )
Structure Level Pattern Image Note
TS28: dentate gyrus granule cell layer Weak Regionally restricted 4d ArhGAP15-/- Authors report significant reduction of expressing punctae compared with wild-type.

Specimen not shown Wild-type: postnatal day 30 (more )
Structure Level Pattern Image Note
TS28: dentate gyrus granule cell layer Present Regionally restricted

Specimen not shown ArhGAP15-/-: postnatal day 30; Arhgap15tm1Ehi/Arhgap15tm1Ehi (more )
Structure Level Pattern Image Note
TS28: dentate gyrus granule cell layer Weak Regionally restricted Authors report significant reduction of expressing punctae compared with wild-type.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/18/2025
MGI 6.24
The Jackson Laboratory