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Gene Expression Data
Assay Details
Assay
Reference: J:29655 Li L, et al., Dermo-1: a novel twist-related bHLH protein expressed in the developing dermis. Dev Biol. 1995 Nov;172(1):280-92
Assay type: RNA in situ
MGI Accession ID: MGI:6112004
Gene symbol: Twist2
Gene name: twist basic helix-loop-helix transcription factor 2
Probe: Dermo-1 probe
Probe preparation: Antisense labelled with digoxigenin RNA
Visualized with: Alkaline phosphatase
Results
Specimen not shown E10.5: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: embryo Weak Regionally restricted Low level of expression over body surface.

Specimen 6A: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: limb mesenchyme Present Regionally restricted 6A Expression in mesenchymal condensations in proximal part of limb bud.
TS20: vibrissa Strong Regionally restricted 6A Intense expression in whisker pads.

Specimen 6B: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: embryo Present Regionally restricted 6B Authors state that pattern of expression reflected somite organization.

Specimen 6C: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: forelimb digit Present 6C Expression in digit zones of both forelimb and hindlimb.
TS21: hindlimb digit Present 6C Expression in digit zones of both forelimb and hindlimb.
TS21: vibrissa Strong Regionally restricted 6C Expression intensified in whisker pads at this stage.
TS21: vibrissa epidermal component Absent 6C No expression in central epidermal cells of each vibrissa.
TS21: hair follicle Absent 6C

Specimen 6D: embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS23: hair follicle Present Widespread 6D Expression in hair follicles over entire body.

Specimen 6E: embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS23: skin Strong Regionally restricted 6E High levels of expression in lateral regions, gradually appearing in dorsal regions as skin development proceeds.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
12/30/2025
MGI 6.24
The Jackson Laboratory