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Gene Expression Data
Assay Details
Assay
Reference: J:245622 Madon-Simon M, et al., Defective glucocorticoid receptor signaling and keratinocyte-autonomous defects contribute to skin phenotype of mouse embryos lacking the Hsp90 co-chaperone p23. PLoS One. 2017;12(6):e0180035
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6094211
Gene symbol: Ptges3
Gene name: prostaglandin E synthase 3
Antibody: anti-p23 (JJ3)
Detection system: Secondary antibody
Results
Specimen 2a WT left: embryonic day 18.5 (more )
Structure Level Pattern Image Note
TS26: dermis Present 2a p23 WT left
TS26: hair follicle Present 2a p23 WT left
TS26: epidermis Present Regionally restricted 2a p23 WT left Expression is in basal keratinocytes.
TS26: epidermis granular layer Present Single cells 2a p23 WT left
TS26: epidermis spinous layer Present Single cells 2a p23 WT left
Specimen 2a WT right: embryonic day 18.5 (more )
Structure Level Pattern Image Note
TS26: dermis Present 2a p23 WT right
TS26: hair follicle Present 2a p23 WT right
TS26: epidermis Present Regionally restricted 2a p23 WT right Expression is in basal keratinocytes.
TS26: epidermis granular layer Present Single cells 2a p23 WT right
TS26: epidermis spinous layer Present Single cells 2a p23 WT right
Specimen 2a p23-/- left: embryonic day 18.5; Ptges3Gt(W069F07)Wrst/Ptges3Gt(W069F07)Wrst (more )
Structure Level Pattern Image Note
TS26: skin Absent 2a p23 p23-/- left
Specimen 2a p23-/- right: embryonic day 18.5; Ptges3Gt(W069F07)Wrst/Ptges3Gt(W069F07)Wrst (more )
Structure Level Pattern Image Note
TS26: skin Absent 2a p23 p23-/- right
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
05/14/2024
MGI 6.23 		The Jackson Laboratory