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Gene Expression Data
Assay Details
Assay
Reference: J:173393 Chung SH, et al., Zac1 plays a key role in the development of specific neuronal subsets in the mouse cerebellum. Neural Dev. 2011;6:25
Assay type: Immunohistochemistry
MGI Accession ID: MGI:5912037
Gene symbol: Nrgn
Gene name: neurogranin
Antibody: anti-NG
Detection system: Biotinylated secondary antibody/[Strept]avidin coupled to horseradish peroxidase
Assay notes: Fixative was 4% paraformaldehyde/0.02% glutaraldehyde with a post-fix in 4% paraformaldehyde.
Results
Specimen 7A: postnatal adult (more )
Structure Level Pattern Image Note
TS28: cerebellum vermis lobule IX Present Single cells 7A , 7C Expression is in Golgi interneurons.
Specimen 7B: postnatal adult; Plagl1tm1Jour/Plagl1+ (more )
Note: Zac1+m/- heterozygotes are effectively Zac1 null mutants due to maternal imprinting of the Plagl1 locus.
Structure Level Pattern Image Note
TS28: cerebellum vermis lobule IX Present Single cells 7B , 7D The number of expressing cells is reduced in this mutant (approximately 63% of that of wild-type).
Specimen 7E: postnatal adult (more )
Structure Level Pattern Image Note
TS28: cerebellum vermis lobule V Present Single cells 7E Expression is in Golgi interneurons.
TS28: cerebellum vermis lobule VI Present Single cells 7E Expression is in Golgi interneurons.
Specimen 7F: postnatal adult; Plagl1tm1Jour/Plagl1+ (more )
Note: Zac1+m/- heterozygotes are effectively Zac1 null mutants due to maternal imprinting of the Plagl1 locus.
Structure Level Pattern Image Note
TS28: cerebellum vermis lobule V Present Single cells 7F Expression in this mutant is the same as in wild-type.
TS28: cerebellum vermis lobule VI Present Single cells 7F Expression in this mutant is the same as in wild-type.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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12/30/2025
MGI 6.24 		The Jackson Laboratory