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Gene Expression Data
Assay Details
Assay
Reference: J:173393 Chung SH, et al., Zac1 plays a key role in the development of specific neuronal subsets in the mouse cerebellum. Neural Dev. 2011;6:25
Assay type: Immunohistochemistry
MGI Accession ID: MGI:5912014
Gene symbol: Tbr1
Gene name: T-box brain transcription factor 1
Antibody: anti-Tbr1
Detection system: Biotinylated secondary antibody/[Strept]avidin coupled to horseradish peroxidase
Assay notes: Fixative was 4% paraformaldehyde/0.02% glutaraldehyde with a post-fix in 4% paraformaldehyde.
Results
Specimen 1B: embryonic day 11.0 (more )
Structure Level Pattern Image Note
TS18: cerebellum primordium Absent 1B
TS18: hindbrain ventricular layer Absent 1B
TS18: rhombic lip Absent 1B
Specimen 1D: embryonic day 12.0 (more )
Structure Level Pattern Image Note
TS20: cerebellum primordium Present Regionally restricted 1D Expression is in a subpial stream of cells at the dorsal surface of the cerebellar anlage.
Specimen 1F: embryonic day 13.0 (more )
Structure Level Pattern Image Note
TS21: cerebellum Present Regionally restricted 1F Expression is in a cluster in the nuclear transitory zone.
Specimen 1H: postnatal day 0 (more )
Structure Level Pattern Image Note
TS27: cerebellum Present Regionally restricted 1H Expression is in the medial nuclei.
Specimen S1A: embryonic day 18.5 (more )
Structure Level Pattern Image Note
TS26: cerebellum Present Regionally restricted S1A Expression is in the nuclear transitory zone.
Specimen S1B: embryonic day 18.5; Plagl1tm1Jour/Plagl1+ (more )
Note: Zac1+m/- heterozygotes are effectively Zac1 null mutants due to maternal imprinting of the Plagl1 locus.
Structure Level Pattern Image Note
TS26: cerebellum Present S1B Expression in this mutant is the same as in wild-type.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory