Gene Expression Data
Assay Details
Assay
|
Reference:
|
J:18694
Salbaum JM, et al., Embryonic expression pattern of amyloid protein precursor suggests a role in differentiation of specific subsets of neurons. J Exp Zool. 1994 Jun 1;269(2):116-27
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Assay type:
|
Immunohistochemistry
|
MGI Accession ID:
|
MGI:5911637
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Gene symbol:
|
App
|
Gene name:
|
amyloid beta precursor protein
|
Antibody:
|
anti-APP
|
Detection system:
|
Secondary antibody coupled to alkaline phosphatase
|
|
Results
|
Specimen
1A:
embryonic day 9.5
(more )
Specimen
1A:
(close )
Genetic Background:
|
FVB/N
|
Age:
|
embryonic day 9.5
|
Sex:
|
Not Specified
|
Type:
|
section
|
Fixation:
|
4% Paraformaldehyde
|
Embedding:
|
Cryosection
|
Structure |
Level |
Pattern |
Image |
Note |
TS15: future hindbrain |
Present |
Regionally restricted |
1A
|
Expressed in the mantle layer of the ventral hindbrain, concentrated close to the midline as a cluster that extended laterally to form a layer.
|
TS15: trigeminal placode |
Present |
|
1A
|
|
Specimen
1B:
embryonic day 9.5
(more )
Specimen
1B:
(close )
Genetic Background:
|
FVB/N
|
Age:
|
embryonic day 9.5
|
Sex:
|
Not Specified
|
Type:
|
section
|
Fixation:
|
4% Paraformaldehyde
|
Embedding:
|
Cryosection
|
Structure |
Level |
Pattern |
Image |
Note |
TS15: neural tube floor plate |
Present |
|
1B
|
|
TS15: neural tube lateral wall |
Present |
Regionally restricted |
1B
|
Expressed in the ventral-lateral area of the spinal cord and the future ventral horn. Only a few positive cells in the ventral-lateral intermediate zone. No expression in the ventricular zone.
|
Specimen
1D:
embryonic day 10.5
(more )
Specimen
1D:
(close )
Genetic Background:
|
FVB/N
|
Age:
|
embryonic day 10.5
|
Sex:
|
Not Specified
|
Type:
|
section
|
Fixation:
|
4% Paraformaldehyde
|
Embedding:
|
Cryosection
|
Structure |
Level |
Pattern |
Image |
Note |
TS17: hindbrain |
Present |
Regionally restricted |
1D
|
Expressed in the mantle layer cells of the ventral part. Concentrated close to the midline in an area that will give rise to the trigeminal nucleus.
|
TS17: trigeminal ganglion |
Present |
|
1D
|
|
Specimen
1E:
embryonic day 10.5
(more )
Specimen
1E:
(close )
Genetic Background:
|
FVB/N
|
Age:
|
embryonic day 10.5
|
Sex:
|
Not Specified
|
Type:
|
section
|
Fixation:
|
4% Paraformaldehyde
|
Embedding:
|
Cryosection
|
Specimen
1F:
embryonic day 10.5
(more )
Specimen
1F:
(close )
Genetic Background:
|
FVB/N
|
Age:
|
embryonic day 10.5
|
Sex:
|
Not Specified
|
Type:
|
section
|
Fixation:
|
4% Paraformaldehyde
|
Embedding:
|
Cryosection
|
Structure |
Level |
Pattern |
Image |
Note |
TS17: hindbrain |
Present |
Regionally restricted |
1F
|
Expressed in the ventral and lateral areas, and the cranial nerve rootlets.
|
TS17: vagus ganglion |
Present |
|
1F
|
|
Specimen
1G:
embryonic day 10.5
(more )
Specimen
1G:
(close )
Genetic Background:
|
FVB/N
|
Age:
|
embryonic day 10.5
|
Sex:
|
Not Specified
|
Type:
|
section
|
Fixation:
|
4% Paraformaldehyde
|
Embedding:
|
Cryosection
|
Specimen
1H:
embryonic day 10.5
(more )
Specimen
1H:
(close )
Genetic Background:
|
FVB/N
|
Age:
|
embryonic day 10.5
|
Sex:
|
Not Specified
|
Type:
|
section
|
Fixation:
|
4% Paraformaldehyde
|
Embedding:
|
Cryosection
|
Specimen
1I:
embryonic day 10.5
(more )
Specimen
1I:
(close )
Genetic Background:
|
FVB/N
|
Age:
|
embryonic day 10.5
|
Sex:
|
Not Specified
|
Type:
|
section
|
Fixation:
|
4% Paraformaldehyde
|
Embedding:
|
Cryosection
|
Specimen
2A:
embryonic day 12.5
(more )
Specimen
2A:
(close )
Genetic Background:
|
FVB/N
|
Age:
|
embryonic day 12.5
|
Sex:
|
Not Specified
|
Type:
|
section
|
Fixation:
|
4% Paraformaldehyde
|
Embedding:
|
Cryosection
|
Specimen
2B:
embryonic day 12.5
(more )
Specimen
2B:
(close )
Genetic Background:
|
FVB/N
|
Age:
|
embryonic day 12.5
|
Sex:
|
Not Specified
|
Type:
|
section
|
Fixation:
|
4% Paraformaldehyde
|
Embedding:
|
Cryosection
|
Specimen
2C:
embryonic day 12.5
(more )
Specimen
2C:
(close )
Genetic Background:
|
FVB/N
|
Age:
|
embryonic day 12.5
|
Sex:
|
Not Specified
|
Type:
|
section
|
Fixation:
|
4% Paraformaldehyde
|
Embedding:
|
Cryosection
|
Specimen
2D:
embryonic day 12.5
(more )
Specimen
2D:
(close )
Genetic Background:
|
FVB/N
|
Age:
|
embryonic day 12.5
|
Sex:
|
Not Specified
|
Type:
|
section
|
Fixation:
|
4% Paraformaldehyde
|
Embedding:
|
Cryosection
|
Specimen
2E:
embryonic day 13.5
(more )
Specimen
2E:
(close )
Genetic Background:
|
FVB/N
|
Age:
|
embryonic day 13.5
|
Sex:
|
Not Specified
|
Type:
|
section
|
Fixation:
|
4% Paraformaldehyde
|
Embedding:
|
Cryosection
|
Specimen
2F:
embryonic day 13.5
(more )
Specimen
2F:
(close )
Genetic Background:
|
FVB/N
|
Age:
|
embryonic day 13.5
|
Sex:
|
Not Specified
|
Type:
|
section
|
Fixation:
|
4% Paraformaldehyde
|
Embedding:
|
Cryosection
|
Structure |
Level |
Pattern |
Image |
Note |
TS21: vagus ganglion |
Present |
|
2F
|
Expressed in cells of the dorsal motor nucleus of the vagus nerve.
|
Specimen
2G:
embryonic day 13.5
(more )
Specimen
2G:
(close )
Genetic Background:
|
FVB/N
|
Age:
|
embryonic day 13.5
|
Sex:
|
Not Specified
|
Type:
|
section
|
Fixation:
|
4% Paraformaldehyde
|
Embedding:
|
Cryosection
|
Structure |
Level |
Pattern |
Image |
Note |
TS21: medulla oblongata |
Present |
Regionally restricted |
2G
|
Expressed in cells of the nucleus of the hypoglossal nerve.
|
Specimen
2H:
embryonic day 13.5
(more )
Specimen
2H:
(close )
Genetic Background:
|
FVB/N
|
Age:
|
embryonic day 13.5
|
Sex:
|
Not Specified
|
Type:
|
section
|
Fixation:
|
4% Paraformaldehyde
|
Embedding:
|
Cryosection
|
Specimen
2I:
embryonic day 13.5
(more )
Specimen
2I:
(close )
Genetic Background:
|
FVB/N
|
Age:
|
embryonic day 13.5
|
Sex:
|
Not Specified
|
Type:
|
section
|
Fixation:
|
4% Paraformaldehyde
|
Embedding:
|
Cryosection
|
Specimen
3D:
embryonic day 11.5
(more )
Specimen
3D:
(close )
Genetic Background:
|
FVB/N
|
Age:
|
embryonic day 11.5
|
Sex:
|
Not Specified
|
Type:
|
section
|
Fixation:
|
4% Paraformaldehyde
|
Embedding:
|
Cryosection
|
Specimen
3F:
embryonic day 11.5
(more )
Specimen
3F:
(close )
Genetic Background:
|
FVB/N
|
Age:
|
embryonic day 11.5
|
Sex:
|
Not Specified
|
Type:
|
section
|
Fixation:
|
4% Paraformaldehyde
|
Embedding:
|
Cryosection
|
Structure |
Level |
Pattern |
Image |
Note |
TS19: myelencephalon |
Present |
Regionally restricted |
3F
|
Stronger expression in the dorsal motor nucleus of the vagus (X) nerve, and neurons of the nucleus of hypoglossal (XII) nerve, compared with the cells in the surrounding tissue.
|
TS19: myelencephalon floor plate |
Present |
|
3F
|
|
Specimen
3G:
embryonic day 13.5
(more )
Specimen
3G:
(close )
Genetic Background:
|
FVB/N
|
Age:
|
embryonic day 13.5
|
Sex:
|
Not Specified
|
Type:
|
section
|
Fixation:
|
4% Paraformaldehyde
|
Embedding:
|
Cryosection
|
Structure |
Level |
Pattern |
Image |
Note |
TS21: medulla oblongata |
Strong |
Regionally restricted |
3G
|
Expressed in neurons of the nucleus of hypoglossal nerve, and in the dorsal motor nucleus of vagus nerve.
|
Specimen
3H:
embryonic day 13.5
(more )
Specimen
3H:
(close )
Genetic Background:
|
FVB/N
|
Age:
|
embryonic day 13.5
|
Sex:
|
Not Specified
|
Type:
|
section
|
Fixation:
|
4% Paraformaldehyde
|
Embedding:
|
Cryosection
|
Specimen
3I:
embryonic day 13.5
(more )
Specimen
3I:
(close )
Genetic Background:
|
FVB/N
|
Age:
|
embryonic day 13.5
|
Sex:
|
Not Specified
|
Type:
|
section
|
Fixation:
|
4% Paraformaldehyde
|
Embedding:
|
Cryosection
|
Specimen
not shown:
embryonic day 8.5
(more )
Specimen
not shown:
(close )
Genetic Background:
|
FVB/N
|
Age:
|
embryonic day 8.5
|
Sex:
|
Not Specified
|
Type:
|
section
|
Fixation:
|
4% Paraformaldehyde
|
Embedding:
|
Cryosection
|
Specimen
not shown:
embryonic day 9.5
(more )
Specimen
not shown:
(close )
Genetic Background:
|
FVB/N
|
Age:
|
embryonic day 9.5
|
Sex:
|
Not Specified
|
Type:
|
section
|
Fixation:
|
4% Paraformaldehyde
|
Embedding:
|
Cryosection
|
Specimen
not shown:
embryonic day 10.5
(more )
Specimen
not shown:
(close )
Genetic Background:
|
FVB/N
|
Age:
|
embryonic day 10.5
|
Sex:
|
Not Specified
|
Type:
|
section
|
Fixation:
|
4% Paraformaldehyde
|
Embedding:
|
Cryosection
|
Specimen
not shown:
embryonic day 11.5
(more )
Specimen
not shown:
(close )
Genetic Background:
|
FVB/N
|
Age:
|
embryonic day 11.5
|
Sex:
|
Not Specified
|
Type:
|
section
|
Fixation:
|
4% Paraformaldehyde
|
Embedding:
|
Cryosection
|
Specimen
not shown:
embryonic day 12.5
(more )
Specimen
not shown:
(close )
Genetic Background:
|
FVB/N
|
Age:
|
embryonic day 12.5
|
Sex:
|
Not Specified
|
Type:
|
section
|
Fixation:
|
4% Paraformaldehyde
|
Embedding:
|
Cryosection
|
Structure |
Level |
Pattern |
Image |
Note |
TS20: hindbrain |
Present |
Clusters |
|
Expressed in the clustered cells in the neural tube, which begin to form the motor nuclei of the cranial nerves.
|
TS20: sympathetic ganglion |
Present |
|
|
|
Specimen
not shown:
embryonic day 13.5
(more )
Specimen
not shown:
(close )
Genetic Background:
|
FVB/N
|
Age:
|
embryonic day 13.5
|
Sex:
|
Not Specified
|
Type:
|
section
|
Fixation:
|
4% Paraformaldehyde
|
Embedding:
|
Cryosection
|
|