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Gene Expression Data
Assay Details
Assay
Reference: J:198100 Andreeva V, et al., Rb1 mRNA expression in developing mouse teeth. Gene Expr Patterns. 2012 Mar-Apr;12(3-4):130-5
Assay type: RNA in situ
MGI Accession ID: MGI:5910415
Gene symbol: Runx2
Gene name: runt related transcription factor 2
Probe: Runx probe9
Probe preparation: Antisense labelled with digoxigenin RNA
Results
Specimen 1D: postnatal day 0 (more )
Structure Level Pattern Image Note
TS27: head bone Present Regionally restricted 1D Expression is in the prefrontal bone.
Specimen 2B: embryonic day 12.5 (more )
Note: Bud stage tooth.
Structure Level Pattern Image Note
TS20: jaw Strong Regionally restricted 2B Expression is in the molar mesenchyme.
Specimen 2E: embryonic day 14.5 (more )
Note: Cap stage tooth.
Structure Level Pattern Image Note
TS22: molar mesenchyme Strong 2E
Specimen 3B: embryonic day 16.5 (more )
Note: Bell stage tooth. B1 and B2 are higher magnifications of the boxed areas in B.
Structure Level Pattern Image Note
TS24: molar mesenchyme Strong Regionally restricted 3B , 3B1 , 3B2 Expression is in pre-odontoblasts and diffuse expression dental pulp cells.
TS24: dental sac Present 3B , 3B2 , 3B1
Specimen 4B: postnatal day 0 (more )
Note: B1 is a higher magnification of the boxed area in B.
Structure Level Pattern Image Note
TS27: jaw Present Regionally restricted 4B , 4B1 Expression is in osteoblasts in the alveolar bone that surrounds the tooth.
TS27: molar mesenchyme Weak Regionally restricted 4B , 4B1 Expression is in differentiated odontoblasts.
TS27: molar dental pulp Weak 4B1 , 4B
TS27: alveolar process Weak 4B , 4B1
Specimen 5B: postnatal day 0 (more )
Note: B1 and B2 are higher magnifications of the boxed areas in B.
Structure Level Pattern Image Note
TS27: incisor dental papilla Present 5B2 , 5B1 , 5B
TS27: incisor mesenchyme Present Regionally restricted 5B , 5B2 , 5B1 Expression is in pre-odontoblasts.
TS27: jaw Strong Regionally restricted 5B , 5B2 , 5B1 Expression is in alveolar bone that surrounds the tooth.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/18/2025
MGI 6.24 		The Jackson Laboratory