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Gene Expression Data
Assay Details
Assay
Reference: J:240595 Mao H, et al., Mouse models of Casc3 reveal developmental functions distinct from other components of the exon junction complex. RNA. 2017 Jan;23(1):23-31
Assay type: RT-PCR
MGI Accession ID: MGI:5906360
Gene symbol: Casc3
Gene name: exon junction complex subunit
Probe: Mm01296308_m1
Assay notes: Quantitative RT-PCR. Relative expression is shown in a graph normalized to Gapdh expression.
Results Image: 1N
 Sample Information Bands Other Sample Information
Lane AgeStructure Size Not Specified Amount Genetic BackgroundMutant Allele(s)Sex
+/+ E16.5 TS24: cerebral cortex Present Not Specified involves: 129P2/OlaHsd * C57BL/6J Not Specified
Casc3Gt(RRU345)Byg/+ E16.5 TS24: cerebral cortex Present (a) Not Specified involves: 129P2/OlaHsd * C57BL/6J Casc3Gt(RRU345)Byg/Casc3+Not Specified
Casc3Gt(RRU345)Byg/Casc3Gt(RRU345)Byg E16.5 TS24: cerebral cortex Present (b) Not Specified involves: 129P2/OlaHsd * C57BL/6J Casc3Gt(RRU345)Byg/Casc3Gt(RRU345)BygNot Specified
Notes:
(a) There was a 52%-54% significant reduction in expression in the heterozygote.
(b) There was a 90%-95% significant reduction in expression in this mutant.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
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