About   Help   FAQ
Gene Expression Data
Assay Details
Assay
Reference: J:206212 Leung KK, et al., Angiotensin II type 2 receptor regulates the development of pancreatic endocrine cells in mouse embryos. Dev Dyn. 2014 Mar;243(3):415-27
Assay type: Immunohistochemistry
MGI Accession ID: MGI:5904279
Gene symbol: Ins1
Gene name: insulin I
Antibody: anti-insulin
Detection system: Secondary antibody coupled to Alexa Fluor 488
Assay notes: The specificity of the antibody used was not detailed; both family members have been annotated.
Results
Specimen 2 e12.5 top: embryonic day 12.5 (more )
Note: Double labeled: green - Ins1 and Ins2; red - Agtr1a (assay MGI:5904277).
Structure Level Pattern Image Note
TS20: pancreas parenchyma Present Single cells 2_top e12.5 Expression is in beta cell progenitors.
Specimen 2 e15.5 top: embryonic day 15.5 (more )
Note: Double labeled: green - Ins1 and Ins2; red - Agtr1a (assay MGI:5904277).
Structure Level Pattern Image Note
TS23: islets of Langerhans Present Regionally restricted 2_top e15.5 Expression is in beta cells.
Specimen 2 e17.5 top: embryonic day 17.5 (more )
Note: Double labeled: green - Ins1 and Ins2; red - Agtr1a (assay MGI:5904277).
Structure Level Pattern Image Note
TS25: islets of Langerhans Present Regionally restricted 2_top e17.5 Expression is in clusters of beta cells.
Specimen 2 neonate top: postnatal newborn (more )
Note: Double labeled: green - Ins1 and Ins2; red - Agtr1a (assay MGI:5904277).
Structure Level Pattern Image Note
TS27: islets of Langerhans Present Regionally restricted 2_top neonate Expression is in beta cells.
Specimen 2 e12.5 bottom: embryonic day 12.5 (more )
Note: Double labeled: green - Ins1 and Ins2; red - Agtr2 (assay MGI:5904278).
Structure Level Pattern Image Note
TS20: pancreas parenchyma Present Single cells 2_bottom e12.5 , 2_bottom e12.5 insert Expression is in beta cell progenitors.
Specimen 2 e15.5: embryonic day 15.5 (more )
Note: Double labeled: green - Ins1 and Ins2; red - Agtr2 (assay MGI:5904278).
Structure Level Pattern Image Note
TS23: islets of Langerhans Present Regionally restricted 2_bottom e15.5 insert , 2_bottom e15.5 Expression is in beta cells.
Specimen 2 e17.5: embryonic day 17.5 (more )
Note: Double labeled: green - Ins1 and Ins2; red - Agtr2 (assay MGI:5904278).
Structure Level Pattern Image Note
TS25: islets of Langerhans Present Regionally restricted 2_bottom e17.5 insert , 2_bottom e17.5 Expression is in clusters of beta cells.
Specimen 2 neonate: postnatal newborn (more )
Note: Double labeled: green - Ins1 and Ins2; red - Agtr2 (assay MGI:5904278).
Structure Level Pattern Image Note
TS27: islets of Langerhans Present Regionally restricted 2_bottom neonate insert , 2_bottom neonate Expression is in beta cells.
Specimen S2 islet top: postnatal adult (more )
Note: Double labeled: green - Ins1 and Ins2; red - Agtr1a (assay MGI:5904277).
Structure Level Pattern Image Note
TS28: islets of Langerhans Present Regionally restricted S2_top left Expression is in beta cells.
Specimen S2 islet bottom: postnatal adult (more )
Note: Double labeled: green - Ins1 and Ins2; red - Agtr2 (assay MGI:5904278).
Structure Level Pattern Image Note
TS28: islets of Langerhans Present Regionally restricted S2_bottom left Expression is in beta cells.
Specimen S2 kidney top: postnatal adult (more )
Note: Double labeled: green - Ins1 and Ins2; red - Agtr1a (assay MGI:5904277).
Structure Level Pattern Image Note
TS28: metanephros Absent S2_top center
Specimen S2 kidney bottom: postnatal adult (more )
Note: Double labeled: green - Ins1 and Ins2; red - Agtr2 (assay MGI:5904278).
Structure Level Pattern Image Note
TS28: metanephros Absent S2_bottom center
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
03/25/2025
MGI 6.24 		The Jackson Laboratory