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Gene Expression Data
Assay Details
Assay
Reference: J:203003 Janke A, et al., A new look at cytoskeletal NOS-1 and beta-dystroglycan changes in developing muscle and brain in control and mdx dystrophic mice. Dev Dyn. 2013 Dec;242(12):1369-81
Assay type: Immunohistochemistry
MGI Accession ID: MGI:5903857
Gene symbol: Nos1
Gene name: nitric oxide synthase 1, neuronal
Antibody: anti-NOS1 (sc-1025)
Detection system: Secondary antibody coupled to Alexa Fluor 488
Results
Specimen 3A P10 control: postnatal day 10 (more )
Structure Level Pattern Image Note
TS28: quadriceps femoris muscle Present 3A NOS-1 control P10 Expression is at the periphery of fibers.

Specimen 3A P10 mdx: postnatal day 10; Dmdmdx/Dmdmdx (more )
Structure Level Pattern Image Note
TS28: quadriceps femoris muscle Present 3A NOS-1 mdx P10 Expression is localized inside the membrane of dystrophic fibers.

Specimen 3A P28 control: postnatal day 28 (more )
Structure Level Pattern Image Note
TS28: quadriceps femoris muscle Present 3A NOS-1 control P28

Specimen 3A P28 mdx: postnatal day 28; Dmdmdx/Dmdmdx (more )
Structure Level Pattern Image Note
TS28: quadriceps femoris muscle Present 3A NOS-1 mdx P28 Expression is localized inside the membrane of dystrophic fibers.

Specimen 3B P10 control: postnatal day 10 (more )
Structure Level Pattern Image Note
TS28: diaphragm Present 3B NOS-1 control P10

Specimen 3B P10 mdx: postnatal day 10; Dmdmdx/Dmdmdx (more )
Structure Level Pattern Image Note
TS28: diaphragm Present 3B NOS-1 mdx P10 Expression is localized inside the membrane of dystrophic fibers.

Specimen 3B P28 control: postnatal day 28 (more )
Structure Level Pattern Image Note
TS28: diaphragm Present 3B NOS-1 control P28

Specimen 3B P28 mdx: postnatal day 28; Dmdmdx/Dmdmdx (more )
Structure Level Pattern Image Note
TS28: diaphragm Present 3B NOS-1 mdx P28 Expression is localized inside the membrane of dystrophic fibers.

Specimen 3C P10 control: postnatal day 10 (more )
Structure Level Pattern Image Note
TS28: muscle tissue Present 3C NOS-1 control x100 , 3C NOS-1 control P10

Specimen 3C P28 control: postnatal day 28 (more )
Structure Level Pattern Image Note
TS28: muscle tissue Present 3C NOS-1 control P28

Specimen 3C P28 mdx: postnatal day 28; Dmdmdx/Dmdmdx (more )
Structure Level Pattern Image Note
TS28: muscle tissue Present 3C NOS-1 mdx P28 Expression is localized inside the membrane of dystrophic fibers.

Specimen 5B right: postnatal day 28 (more )
Structure Level Pattern Image Note
TS28: cerebellum Purkinje cell layer Present Diffuse 5B right panel
TS28: cerebellum granule cell layer Present Diffuse 5B right panel
TS28: cerebellum molecular layer Present Diffuse 5B right panel

Specimen 5C left: postnatal day 28 (more )
Structure Level Pattern Image Note
TS28: cerebellum Purkinje cell layer Present 5C left panel

Specimen 5C right: postnatal day 28; Dmdmdx/Dmdmdx (more )
Structure Level Pattern Image Note
TS28: cerebellum Purkinje cell layer Present 5C right panel

Specimen not shown E18: embryonic day 18.0 (more )
Structure Level Pattern Image Note
TS26: diaphragm Present Expression is at the sarcoplasm.
TS26: quadriceps femoris muscle Present Expression is at the sarcoplasm.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/25/2025
MGI 6.24
The Jackson Laboratory