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Gene Expression Data
Assay Details
Assay
Reference: J:69393 Naruse-Nakajima C, et al., Involvement of EphA2 in the formation of the tail notochord via interaction with ephrinA1. Mech Dev. 2001 Apr;102(1-2):95-105
Assay type: RNA in situ
MGI Accession ID: MGI:5903471
Gene symbol: T
Gene name: brachyury, T-box transcription factor T
Probe: T probe28
Probe preparation: Antisense labelled with digoxigenin RNA
Visualized with: Alkaline phosphatase
Results
Specimen 7A: embryonic day 11.5; Epha2Gt(ROSABetageo)CN3Yiw/Epha2+ (more )
Structure Level Pattern Image Note
TS19: notochord Present 7A

Specimen 7B: embryonic day 11.5; Epha2Gt(ROSABetageo)CN3Yiw/Epha2Gt(ROSABetageo)CN3Yiw (more )
Structure Level Pattern Image Note
TS19: notochord Present Regionally restricted 7B Rostral notochord formed normally.

Specimen 7C: embryonic day 11.5; Epha2Gt(ROSABetageo)CN3Yiw/Epha2Gt(ROSABetageo)CN3Yiw (more )
Structure Level Pattern Image Note
TS19: notochord Present Regionally restricted 7C Authors report abnormal notochord formation in homozygous embryos as compared with heteriozygous embryos. Caudal notochord was bifurcated.

Specimen 7D: embryonic day 12.5; Epha2Gt(ROSABetageo)CN3Yiw/Epha2+ (more )
Structure Level Pattern Image Note
TS20: notochord Present 7D

Specimen 7E: embryonic day 12.5; Epha2Gt(ROSABetageo)CN3Yiw/Epha2Gt(ROSABetageo)CN3Yiw (more )
Structure Level Pattern Image Note
TS20: notochord Present Regionally restricted 7E Authors report abnormal notochord formation in homozygous embryos as compared with heteriozygous embryos. Rostral notochord formed normally.

Specimen 7F: embryonic day 12.5; Epha2Gt(ROSABetageo)CN3Yiw/Epha2Gt(ROSABetageo)CN3Yiw (more )
Structure Level Pattern Image Note
TS20: notochord Present Regionally restricted 7F Rostral notochord formed normally.

Specimen 7G: embryonic day 12.5; Epha2Gt(ROSABetageo)CN3Yiw/Epha2+ (more )
Structure Level Pattern Image Note
TS20: notochord Present 7G

Specimen 7H: embryonic day 12.5; Epha2Gt(ROSABetageo)CN3Yiw/Epha2Gt(ROSABetageo)CN3Yiw (more )
Structure Level Pattern Image Note
TS20: notochord Present Regionally restricted 7H Authors report abnormal notochord formation in homozygous embryos as compared with heteriozygous embryos. Caudal notochord was bifurcated. Bifurcated notochords were abnormally intertwined.

Specimen 7I: embryonic day 12.5; Epha2Gt(ROSABetageo)CN3Yiw/Epha2Gt(ROSABetageo)CN3Yiw (more )
Structure Level Pattern Image Note
TS20: notochord Present Regionally restricted 7I Caudal notochord was bifurcated.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/18/2025
MGI 6.24
The Jackson Laboratory