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Gene Expression Data
Assay Details
Assay
Reference: J:46130 Nakayama A, et al., Mutations in microphthalmia, the mouse homolog of the human deafness gene MITF, affect neuroepithelial and neural crest-derived melanocytes differently. Mech Dev. 1998 Jan;70(1-2):155-66
Assay type: Immunohistochemistry
MGI Accession ID: MGI:5898558
Gene symbol: Mitf
Gene name: melanogenesis associated transcription factor
Antibody: anti-Mitf
Results
Specimen 4A: embryonic day 10.5 (more )
Note: Double labeled: red or yellow - Mitf; green - Kit (assay MGI:5898560).
Structure Level Pattern Image Note
TS17: head mesenchyme derived from neural crest Present Regionally restricted 4A
Specimen 4B: embryonic day 10.5 (more )
Note: Double labeled: red or yellow - Mitf; green - Kit (assay MGI:5898560).
Structure Level Pattern Image Note
TS17: trunk mesenchyme derived from neural crest Present Regionally restricted 4B
Specimen 4C: embryonic day 11.5 (more )
Note: Double labeled: red or yellow - Mitf; green - Kit (assay MGI:5898560).
Structure Level Pattern Image Note
TS19: tail mesenchyme derived from neural crest Present Regionally restricted 4C
Specimen 4D: embryonic day 10.5; Mitfmi-ew/Mitfmi-ew (more )
Note: Double labeled: red or yellow - Mitf; green - Kit (assay MGI:5898560).
Structure Level Pattern Image Note
TS17: head mesenchyme derived from neural crest Absent 4D
Specimen 4E: embryonic day 10.5; Mitfmi-ew/Mitfmi-ew (more )
Note: Double labeled: red or yellow - Mitf; green - Kit (assay MGI:5898560).
Structure Level Pattern Image Note
TS17: trunk mesenchyme derived from neural crest Absent 4E
Specimen 4F: embryonic day 11.5; Mitfmi-ew/Mitfmi-ew (more )
Note: Double labeled: red or yellow - Mitf; green - Kit (assay MGI:5898560).
Structure Level Pattern Image Note
TS19: tail mesenchyme derived from neural crest Absent 4F
Specimen 8A: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: pigmented retinal epithelium Present Regionally restricted 8A Predominantly nuclear expression in monolayer of retinal pigmented epithelium cells.
Specimen 8C: embryonic day 14.5; MitfMi-wh/MitfMi-wh (more )
Structure Level Pattern Image Note
TS22: pigmented retinal epithelium Present Regionally restricted 8C Predominantly nuclear expression in more cells than in wild type. Retinal pigmented epithelium mildly thickened.
Specimen 8D: embryonic day 14.5; MitfMi/MitfMi (more )
Structure Level Pattern Image Note
TS22: pigmented retinal epithelium Present Regionally restricted 8D Predominantly nuclear expression in nuclei and cytoplasm of cells in prominently thickened retinal pigmented epithelium.
Specimen 8E: embryonic day 14.5; Mitfmi-ew/Mitfmi-ew (more )
Structure Level Pattern Image Note
TS22: pigmented retinal epithelium Present Regionally restricted 8E Predominantly nuclear expression in nuclei and cytoplasm of cells in prominently thickened retinal pigmented epithelium.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory