About   Help   FAQ
Gene Expression Data
Assay Details
Assay
Reference: J:202662 Du J, et al., Expression of smoothened in mouse embryonic maxillofacial development. Biotech Histochem. 2012 Apr;87(3):187-94
Assay type: RNA in situ
MGI Accession ID: MGI:5898083
Gene symbol: Smo
Gene name: smoothened, frizzled class receptor
Probe: Smo cDNA5
Probe preparation: Antisense labelled with digoxigenin RNA
Results
Specimen 1A: embryonic day 11.0 (more )
Structure Level Pattern Image Note
TS18: 1st branchial arch mandibular component Present 1A
TS18: 1st branchial arch maxillary component Present 1A

Specimen 1B: embryonic day 11.0 (more )
Note: (C) is a higher magnification of the boxed area in (B).
Structure Level Pattern Image Note
TS18: 1st branchial arch mandibular component ectoderm Strong 1B , 1C
TS18: 1st branchial arch maxillary component ectoderm Strong 1B , 1C
TS18: 1st branchial arch mandibular component mesenchyme Present Regionally restricted 1B , 1C Expression was weaker in Meckel's cartilage than in the mesenchyme surrounding it.
TS18: 1st branchial arch maxillary component mesenchyme Present Regionally restricted 1B , 1C Expression was weaker in Meckel's cartilage than in the mesenchyme surrounding it.

Specimen 1D: embryonic day 12.5 (more )
Note: (F) is a higher magnification of the boxed area in (E).
Structure Level Pattern Image Note
TS20: mandible primordium Present 1D
TS20: maxillary process epithelium Present 1D
TS20: maxillary process mesenchyme Present 1D
TS20: vibrissa follicle Absent 1D

Specimen 1E: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: maxillary process epithelium Strong 1F , 1E
TS20: mandibular process Strong Regionally restricted 1E , 1F Expression is stronger in the ectoderm.
TS20: mandibular process mesenchyme Present 1F , 1E
TS20: maxillary process mesenchyme Present 1F , 1E
TS20: Meckel's cartilage Weak 1E , 1F

Specimen not shown: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: lower jaw Absent
TS22: upper jaw Absent


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
03/25/2025
MGI 6.24
The Jackson Laboratory