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Gene Expression Data
Assay Details
Assay
Reference: J:172983 Kobayashi H, et al., Six1 and Six4 are essential for Gdnf expression in the metanephric mesenchyme and ureteric bud formation, while Six1 deficiency alone causes mesonephric-tubule defects. Mech Dev. 2007 Apr;124(4):290-303
Assay type: Immunohistochemistry
MGI Accession ID: MGI:5828469
Gene symbol: Cdh1
Gene name: cadherin 1
Antibody: anti-E-Cadherin
Detection system: horseradish peroxidase
Results
Specimen 2E: embryonic day 11.5; Six1tm1Kwk/Six1+, Six4tm1Kwk/Six4+ (more )
Structure Level Pattern Image Note
TS19: nephric duct Present 2E Expreesion in Wolffian duct.
TS19: ureteric bud Present Regionally restricted 2E Ureteric bud is branched.
Specimen 2F: embryonic day 11.5; Six1tm1Kwk/Six1tm1Kwk (more )
Structure Level Pattern Image Note
TS19: nephric duct Present 2F Expression in Wolffian duct.
TS19: ureteric bud Present Regionally restricted 2F Ureteric buds are short and unbranched.
Specimen 2G: embryonic day 11.5; Six1tm1Kwk/Six1tm1Kwk (more )
Structure Level Pattern Image Note
TS19: nephric duct Present 2G Expression in Wolffian duct.
TS19: ureteric bud Moderate Regionally restricted 2G Ureteric buds are short and unbranched.
Specimen 2H: embryonic day 11.5; Six1tm2Kwk/Six1tm2Kwk (more )
Structure Level Pattern Image Note
TS19: nephric duct Present 2H Expression in Wolffian duct.
TS19: ureteric bud Absent 2H
Specimen 5J: embryonic day 11.5; Six1tm1Kwk/Six1+, Six4tm1Kwk/Six4+ (more )
Structure Level Pattern Image Note
TS19: mesonephric tubule Present Regionally restricted 5J Expression in many mesonephric tubules lined in the craniocaudal direction.
Specimen 5K: embryonic day 11.5; Six1tm1Kwk/Six1tm1Kwk (more )
Structure Level Pattern Image Note
TS19: mesonephric tubule Present Regionally restricted 5K No expression in caudal mesonephric tubules.
Specimen 5L: embryonic day 11.5; Six1tm2Kwk/Six1tm2Kwk (more )
Structure Level Pattern Image Note
TS19: mesonephric tubule Present Regionally restricted 5L No expression in caudal mesonephric tubules.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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12/30/2025
MGI 6.24 		The Jackson Laboratory