Gene Expression Data
Assay Details
|
Assay
|
|
Reference:
|
J:172983
Kobayashi H, et al., Six1 and Six4 are essential for Gdnf expression in the metanephric mesenchyme and ureteric bud formation, while Six1 deficiency alone causes mesonephric-tubule defects. Mech Dev. 2007 Apr;124(4):290-303
|
|
Assay type:
|
RNA in situ
|
|
MGI Accession ID:
|
MGI:5828468
|
|
Gene symbol:
|
Lhx1
|
|
Gene name:
|
LIM homeobox protein 1
|
|
Probe:
|
Lim1 probe4
|
|
Probe preparation:
|
Antisense labelled with digoxigenin RNA
|
|
Visualized with:
|
Alkaline phosphatase
|
|
|
Results
|
Specimen
5D:
(close )
|
Genetic Background:
|
involves: 129P2/OlaHsd
|
|
Mutant Allele(s):
|
Six1tm1Kwk/Six1+ Six4tm1Kwk/Six4+
|
|
Age:
|
embryonic day 10.5
|
|
Sex:
|
Not Specified
|
|
Type:
|
whole mount
|
|
Fixation:
|
Formalin
|
| Structure |
Level |
Pattern |
Image |
Note |
| TS17: mesonephric tubule |
Present |
Regionally restricted |
5D
|
Expression in tubules lined in the cranial caudal direction.
|
Specimen
5E:
(close )
|
Genetic Background:
|
involves: 129P2/OlaHsd
|
|
Mutant Allele(s):
|
Six1tm1Kwk/Six1tm1Kwk
|
|
Age:
|
embryonic day 10.5
|
|
Sex:
|
Not Specified
|
|
Type:
|
whole mount
|
|
Fixation:
|
Formalin
|
| Structure |
Level |
Pattern |
Image |
Note |
| TS17: mesonephric tubule |
Present |
Regionally restricted |
5E
|
No expression in caudal mesonephric tubules.
|
Specimen
5F:
(close )
|
Genetic Background:
|
involves: 129P2/OlaHsd
|
|
Mutant Allele(s):
|
Six1tm2Kwk/Six1tm2Kwk
|
|
Age:
|
embryonic day 10.5
|
|
Sex:
|
Not Specified
|
|
Type:
|
whole mount
|
|
Fixation:
|
Formalin
|
| Structure |
Level |
Pattern |
Image |
Note |
| TS17: mesonephric tubule |
Present |
Regionally restricted |
5F
|
No expression in caudal mesonephric tubules.
|
|