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Gene Expression Data
Assay Details
Assay
Reference: J:172983 Kobayashi H, et al., Six1 and Six4 are essential for Gdnf expression in the metanephric mesenchyme and ureteric bud formation, while Six1 deficiency alone causes mesonephric-tubule defects. Mech Dev. 2007 Apr;124(4):290-303
Assay type: RNA in situ
MGI Accession ID: MGI:5828466
Gene symbol: Pax8
Gene name: paired box 8
Probe: Pax8 probe4
Probe preparation: Antisense labelled with digoxigenin RNA
Visualized with: Alkaline phosphatase
Results
Specimen 4A: embryonic day 9.5 (more )
Structure Level Pattern Image Note
TS15: nephrogenic cord Present 4A Expression in nephrogenic cord.
TS15: nephric duct Present 4A Expression in Wolffian duct.
Specimen 4B: embryonic day 10.0 (more )
Structure Level Pattern Image Note
TS16: nephrogenic cord Present 4B Expression in nephrogenic cord.
TS16: nephric duct Present 4B Expresssion in Wolffian duct.
Specimen 4C: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: mesonephric tubule Present 4C
TS17: nephric duct Present 4C Expression in Wolffian duct.
Specimen 4D: embryonic day 9.5 (more )
Structure Level Pattern Image Note
TS15: nephric duct Present 4D Expression in Wolffian duct.
TS15: genitourinary system Present Regionally restricted 4D No expression in metanephric mesenchyme.
Specimen 4E: embryonic day 10.0; Six1tm1Kwk/Six1+, Six4tm1Kwk/Six4+ (more )
Structure Level Pattern Image Note
TS16: nephric duct Present 4E Expression in Wolffian duct.
TS16: genitourinary system Present Regionally restricted 4E Expression in metanephric mesenchyme.
Specimen 4F: embryonic day 10.0; Six1tm1Kwk/Six1tm1Kwk (more )
Structure Level Pattern Image Note
TS17: nephric duct Present 4F Expression in Wolffian duct.
TS17: metanephric mesenchyme Absent 4F
Specimen 4G: embryonic day 10.0; Six1tm1Kwk/Six1+, Six4tm1Kwk/Six4+ (more )
Structure Level Pattern Image Note
TS16: nephric duct Present 4G Expression in Wolffian duct.
TS16: genitourinary system Present Regionally restricted 4G Expression detected in metanephric mesenchyme.
Specimen 4H: embryonic day 10.0; Six1tm1Kwk/Six1tm1Kwk (more )
Structure Level Pattern Image Note
TS16: nephric duct Present 4H Expression in Wolffian duct.
TS16: genitourinary system Present Regionally restricted 4H Expression detected in metanephric mesenchyme.
Specimen 4I: embryonic day 10.0; Six1tm2Kwk/Six1tm2Kwk (more )
Structure Level Pattern Image Note
TS16: nephric duct Present 4I Expression in Wolffian duct.
TS16: genitourinary system Present Regionally restricted 4I No expression in metanephric mesenchyme.
Specimen 6J: embryonic day 9.5; Six1tm1Kwk/Six1+, Six4tm1Kwk/Six4+ (more )
Structure Level Pattern Image Note
TS15: nephrogenic cord Present 6J Expression in nephrogenic cord.
Specimen 6K: embryonic day 9.5; Six1tm1Kwk/Six1tm1Kwk (more )
Structure Level Pattern Image Note
TS15: nephrogenic cord Present 6K Expression in nephrogenic cord.
Specimen 6L: embryonic day 9.5; Six1tm2Kwk/Six1tm2Kwk (more )
Structure Level Pattern Image Note
TS15: nephrogenic cord Absent 6L No expression in nephrogenic cord.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/18/2025
MGI 6.24 		The Jackson Laboratory