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Gene Expression Data
Assay Details
Assay
Reference: J:172983 Kobayashi H, et al., Six1 and Six4 are essential for Gdnf expression in the metanephric mesenchyme and ureteric bud formation, while Six1 deficiency alone causes mesonephric-tubule defects. Mech Dev. 2007 Apr;124(4):290-303
Assay type: RNA in situ
MGI Accession ID: MGI:5828463
Gene symbol: Gdnf
Gene name: glial cell line derived neurotrophic factor
Probe: Gdnf probe10
Probe preparation: Antisense labelled with digoxigenin RNA
Visualized with: Alkaline phosphatase
Results
Specimen 3M: embryonic day 10.5; Six1tm1Kwk/Six1+, Six4tm1Kwk/Six4+ (more )
Structure Level Pattern Image Note
TS17: metanephric mesenchyme Present 3M
Specimen 3N: embryonic day 10.5; Six1tm1Kwk/Six1tm1Kwk (more )
Structure Level Pattern Image Note
TS17: metanephric mesenchyme Weak 3N
Specimen 3O: embryonic day 10.5; Six1tm2Kwk/Six1tm2Kwk (more )
Structure Level Pattern Image Note
TS17: metanephric mesenchyme Absent 3O
Specimen 4M: embryonic day 10.0; Six1tm1Kwk/Six1+, Six4tm1Kwk/Six4+ (more )
Structure Level Pattern Image Note
TS16: genitourinary system Present Regionally restricted 4M Expression detected in metanephric mesenchyme.
Specimen 4N: embryonic day 10.0; Six1tm1Kwk/Six1tm1Kwk (more )
Structure Level Pattern Image Note
TS16: genitourinary system Present Regionally restricted 4N Expression detected in metanephric mesenchyme.
Specimen 4O: embryonic day 10.0; Six1tm2Kwk/Six1tm2Kwk (more )
Structure Level Pattern Image Note
TS16: genitourinary system Present Regionally restricted 4O Expression detected in metanephric mesenchyme.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/18/2025
MGI 6.24 		The Jackson Laboratory