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Gene Expression Data
Assay Details
Assay
Reference: J:165754 Watanabe T, et al., Transcription factor CHF1/Hey2 regulates coronary vascular maturation. Mech Dev. 2010 Sep-Dec;127(9-12):418-27
Assay type: Immunohistochemistry
MGI Accession ID: MGI:5828247
Gene symbol: Acta2
Gene name: actin alpha 2, smooth muscle, aorta
Antibody: Anti-smooth muscle alpha-Actin (clone 1A4)
Detection system: Biotinylated secondary antibody/[Strept]avidin coupled to horseradish peroxidase
Results
Specimen 3c: embryonic day 18.5 (more )
Structure Level Pattern Image Note
TS26: coronary artery Present 3c Expression in well-developed coronary arteries.
Specimen 3c inset: embryonic day 18.5 (more )
Structure Level Pattern Image Note
TS26: blood vessel smooth muscle Present Regionally restricted 3c inset Expression in distinct circumferential smooth muscle cell layer.
Specimen 3d: embryonic day 18.5; Hey2tm1Mtc/Hey2tm1Mtc (more )
Structure Level Pattern Image Note
TS26: coronary artery Present 3d Expression in dysmorphic blood vessels.
Specimen 3d inset: embryonic day 18.5; Hey2tm1Mtc/Hey2tm1Mtc (more )
Structure Level Pattern Image Note
TS26: blood vessel smooth muscle Present 3d inset Expression in partially disrupted smooth muscle layer.
Specimen 7a: embryonic day 18.5; Hey2tm1Mtc/Hey2tm1Mtc (more )
Structure Level Pattern Image Note
TS26: coronary artery Weak 7a Decreased expression in coronary arteries.
Specimen 7a inset: embryonic day 18.5; Hey2tm1Mtc/Hey2tm1Mtc (more )
Structure Level Pattern Image Note
TS26: coronary artery Weak 7a inset Decreased expression in coronary arteries.
Specimen 7e: embryonic day 18.5 (more )
Structure Level Pattern Image Note
TS26: coronary artery Present 7e
Specimen 7e inset: embryonic day 18.5 (more )
Structure Level Pattern Image Note
TS26: coronary artery Present 7e inset
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory