Casp3 Immunohistochemistry Gene Expression Assay

Gene Expression Data
Assay Details

Assay

Reference:	J:236776 Balmus G, et al., Synthetic lethality between PAXX and XLF in mammalian development. Genes Dev. 2016 Oct 1;30(19):2152-2157
Assay type:	Immunohistochemistry
MGI Accession ID:	MGI:5827966
Gene symbol:	Casp3
Gene name:	caspase 3

Antibody:	anti-Caspase-3 (ab13847)
Assay notes:	The antibody recognizes the cleaved form of the protein.

Results

4A Paxx+/+;Xlf+/+ ©

Specimen 4A Paxx+/+;Xlf+/+: embryonic day 14.5 (more

)

Structure	Level	Pattern	Image	Note
TS22: cerebral cortex	Present		4A Paxx+/+;Xlf+/+

4A Paxx+/+;Xlf-/- ©

Specimen 4A Paxx+/+;Xlf-/-: embryonic day 14.5; Nhej1^tm1Fwa/Nhej1^tm1Fwa (more

)

Structure	Level	Pattern	Image	Note
TS22: cerebral cortex	Present		4A Paxx+/+;Xlf-/-

4A Paxx-/-;Xlf+/+ ©

Specimen 4A Paxx-/-;Xlf+/+: embryonic day 14.5; Paxx^em1Spj/Paxx^em1Spj (more

)

Structure	Level	Pattern	Image	Note
TS22: cerebral cortex	Present		4A Paxx-/-;Xlf+/+

4A Paxx-/-;Xlf-/- ©

Specimen 4A Paxx-/-;Xlf-/-: embryonic day 14.5; Paxx^em1Spj/Paxx^em1Spj, Nhej1^tm1Fwa/Nhej1^tm1Fwa (more

)

Structure	Level	Pattern	Image	Note
TS22: cortical plate	Strong		4A Paxx-/-;Xlf-/-
TS22: cerebral cortex	Present		4A Paxx-/-;Xlf-/-

S7C caspase3 Paxx+/+;Xlf+/+ ©

Specimen S7C Paxx+/+;Xlf+/+: embryonic day 10.5 (more

)

Structure	Level	Pattern	Image	Note
TS17: neural tube	Present		S7C caspase3 Paxx+/+;Xlf+/+

S7C caspase3 Paxx+/+;Xlf-/- ©

Specimen S7C Paxx+/+;Xlf-/-: embryonic day 10.5; Nhej1^tm1Fwa/Nhej1^tm1Fwa (more

)

Structure	Level	Pattern	Image	Note
TS17: neural tube	Present		S7C caspase3 Paxx+/+;Xlf-/-

S7C caspase3 Paxx-/-;Xlf+/+ ©

Specimen S7C Paxx-/-;Xlf+/+: embryonic day 10.5; Paxx^em1Spj/Paxx^em1Spj (more

)

Structure	Level	Pattern	Image	Note
TS17: neural tube	Present		S7C caspase3 Paxx-/-;Xlf+/+

S7C caspase3 Paxx-/-;Xlf-/- ©

Specimen S7C Paxx-/-;Xlf-/-: embryonic day 10.5; Paxx^em1Spj/Paxx^em1Spj, Nhej1^tm1Fwa/Nhej1^tm1Fwa (more

)

Structure	Level	Pattern	Image	Note
TS17: neural tube	Strong		S7C caspase3 Paxx-/-;Xlf-/-

S7D caspase3 Paxx+/+;Xlf+/+ ©

Specimen S7D Paxx+/+;Xlf+/+: embryonic day 14.5 (more

)

Structure	Level	Pattern	Image	Note
TS22: spinal cord	Present		S7D caspase3 Paxx+/+;Xlf+/+

S7D caspase3 Paxx+/+;Xlf-/- ©

Specimen S7D Paxx+/+;Xlf-/-: embryonic day 14.5; Nhej1^tm1Fwa/Nhej1^tm1Fwa (more

)

Structure	Level	Pattern	Image	Note
TS22: spinal cord	Present		S7D caspase3 Paxx+/+;Xlf-/-

S7D caspase3 Paxx-/-;Xlf+/+ ©

Specimen S7D Paxx-/-;Xlf+/+: embryonic day 14.5; Paxx^em1Spj/Paxx^em1Spj (more

)

Structure	Level	Pattern	Image	Note
TS22: spinal cord	Present		S7D caspase3 Paxx-/-;Xlf+/+

S7D caspase3 left Paxx-/-;Xlf-/- ©

Specimen S7D left Paxx-/-;Xlf-/-: embryonic day 14.5; Paxx^em1Spj/Paxx^em1Spj, Nhej1^tm1Fwa/Nhej1^tm1Fwa (more

)

Structure	Level	Pattern	Image	Note
TS22: spinal cord	Strong		S7D caspase3 left Paxx-/-;Xlf-/-

S7D caspase3 right Paxx-/-;Xlf-/- ©

Specimen S7D right Paxx-/-;Xlf-/-: embryonic day 14.5; Paxx^em1Spj/Paxx^em1Spj, Nhej1^tm1Fwa/Nhej1^tm1Fwa (more

)

Structure	Level	Pattern	Image	Note
TS22: spinal cord	Strong		S7D caspase3 right Paxx-/-;Xlf-/-

S8B lung WT ©

Specimen S8B lung WT: embryonic day 14.5 (more

)

Structure	Level	Pattern	Image	Note
TS22: lung	Present		S8B lung WT

S8B lung Paxx-/- ©

Specimen S8B lung Paxx-/-: embryonic day 14.5; Paxx^em1Spj/Paxx^em1Spj (more

)

Structure	Level	Pattern	Image	Note
TS22: lung	Present		S8B lung Paxx-/-	Expression was the same as in wild-type.

S8B lung Xlf-/- ©

Specimen S8B lung Xlf-/-: embryonic day 14.5; Nhej1^tm1Fwa/Nhej1^tm1Fwa (more

)

Structure	Level	Pattern	Image	Note
TS22: lung	Present		S8B lung Xlf-/-	Expression was the same as in wild-type.

S8B lung Paxx-/-;Xlf-/- ©

Specimen S8B lung Paxx-/-;Xlf-/-: embryonic day 14.5; Paxx^em1Spj/Paxx^em1Spj, Nhej1^tm1Fwa/Nhej1^tm1Fwa (more

)

Structure	Level	Pattern	Image	Note
TS22: lung	Present		S8B lung Paxx-/-;Xlf-/-	Expression was the same as in wild-type.

S8B heart WT ©

Specimen S8B heart WT: embryonic day 14.5 (more

)

Structure	Level	Pattern	Image	Note
TS22: heart	Present		S8B heart WT

S8B heart Paxx-/- ©

Specimen S8B heart Paxx-/-: embryonic day 14.5; Paxx^em1Spj/Paxx^em1Spj (more

)

Structure	Level	Pattern	Image	Note
TS22: heart	Present		S8B heart Paxx-/-	Expression was the same as in wild-type.

S8B heart Xlf-/- ©

Specimen S8B heart Xlf-/-: embryonic day 14.5; Nhej1^tm1Fwa/Nhej1^tm1Fwa (more

)

Structure	Level	Pattern	Image	Note
TS22: heart	Present		S8B heart Xlf-/-	Expression was the same as in wild-type.

Specimen S8B heart Paxx-/-;Xlf-/-: embryonic day 14.5; Paxx^em1Spj/Paxx^em1Spj, Nhej1^tm1Fwa/Nhej1^tm1Fwa (more

)

Structure	Level	Pattern	Image	Note
TS22: heart	Present		S8B heart Paxx-/-;Xlf-/-	Expression was the same as in wild-type.

S8B liver WT ©

Specimen S8B liver WT: embryonic day 14.5 (more

)

Structure	Level	Pattern	Image	Note
TS22: liver	Present		S8B liver WT

Specimen S8B liver Paxx-/-: embryonic day 14.5; Paxx^em1Spj/Paxx^em1Spj (more

)

Structure	Level	Pattern	Image	Note
TS22: liver	Present		S8B liver Paxx-/-	Expression was the same as in wild-type.

Specimen S8B liver Xlf-/-: embryonic day 14.5; Nhej1^tm1Fwa/Nhej1^tm1Fwa (more

)

Structure	Level	Pattern	Image	Note
TS22: liver	Present		S8B liver Xlf-/-	Expression was the same as in wild-type.

Specimen S8B liver Paxx-/-;Xlf-/-: embryonic day 14.5; Paxx^em1Spj/Paxx^em1Spj, Nhej1^tm1Fwa/Nhej1^tm1Fwa (more

)

Structure	Level	Pattern	Image	Note
TS22: liver	Present		S8B liver Paxx-/-;Xlf-/-	Expression was the same as in wild-type.

S8B skin WT ©

Specimen S8B skin WT: embryonic day 14.5 (more

)

Structure	Level	Pattern	Image	Note
TS22: skin	Present		S8B skin WT

Specimen S8B skin Paxx-/-: embryonic day 14.5; Paxx^em1Spj/Paxx^em1Spj (more

)

Structure	Level	Pattern	Image	Note
TS22: skin	Present		S8B skin Paxx-/-	Expression was the same as in wild-type.

Specimen S8B skin Xlf-/-: embryonic day 14.5; Nhej1^tm1Fwa/Nhej1^tm1Fwa (more

)

Structure	Level	Pattern	Image	Note
TS22: skin	Present		S8B skin Xlf-/-	Expression was the same as in wild-type.

Specimen S8B skin Paxx-/-;Xlf-/-: embryonic day 14.5; Paxx^em1Spj/Paxx^em1Spj, Nhej1^tm1Fwa/Nhej1^tm1Fwa (more

)

Structure	Level	Pattern	Image	Note
TS22: skin	Present		S8B skin Paxx-/-;Xlf-/-	Expression was the same as in wild-type.

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