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Gene Expression Data
Assay Details
Assay
Reference: J:152922 Golson ML, et al., Jagged1 is a competitive inhibitor of Notch signaling in the embryonic pancreas. Mech Dev. 2009 Aug-Sep;126(8-9):687-99
Assay type: Immunohistochemistry
MGI Accession ID: MGI:5827908
Gene symbol: Sst
Gene name: somatostatin
Results
Specimen E16.5 not shown: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: endocrine pancreas Present Regionally restricted Expression in differentiated endocrine cells.
Specimen 3C: postnatal day 21; Jag1tm1.1Loo/Jag1tm1.1Loo (more )
Note: Authors state that littermate Jag1loxP/loxP and Jag1loxP/+ mice were used as controls in most experiments. Double labeled: red - Sst; green - Ins1 (assay MGI:5827906) and Ins2 (assay MGI:5827907).
Structure Level Pattern Image Note
TS28: pancreas parenchyma Present Regionally restricted 3C
Specimen 3D: postnatal day 21; Jag1tm1.1Loo/Jag1tm1.1Loo, Tg(Foxa3-cre)1Khk/0 (more )
Note: Conditional mutant. Double labeled: red - Sst; green - Ins1 (assay MGI:5827906) and Ins2 (assay MGI:5827907).
Structure Level Pattern Image Note
TS28: pancreas parenchyma Strong Regionally restricted 3D Authors report an approximate 2.5-fold incerase in alpha-cell mass by P21 in mutants vs. controls.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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05/28/2024
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