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Gene Expression Data
Assay Details
Assay
Reference: J:237484 Weidemann M, et al., CFAP157 is a murine downstream effector of FOXJ1 that is specifically required for flagellum morphogenesis and sperm motility. Development. 2016 Dec 15;143(24):4736-4748
Assay type: Immunohistochemistry
MGI Accession ID: MGI:5823968
Gene symbol: Akap3
Gene name: A kinase anchor protein 3
Antibody: AKAP3 antibody (13907-1)
Detection system: Secondary antibody coupled to Alexa Fluor 647
Assay notes: Sections were fixed in either formaldehyde or Bouin's.
Results
Specimen 7Cb: postnatal month 6; Cfap157tm1a(EUCOMM)Hmgu/Cfap157+ (more )
Note: Double labeled: red - Akap3; green - acrosome.
Structure Level Pattern Image Note
TS28: spermatozoon Present Regionally restricted 7Cb Expression is in the fibrous sheath.
Specimen 7Ch: postnatal month 6; Cfap157tm1a(EUCOMM)Hmgu/Cfap157tm1a(EUCOMM)Hmgu (more )
Note: Double labeled: red - Akap3; green - acrosome.
Structure Level Pattern Image Note
TS28: spermatozoon Present Regionally restricted 7Ch Expression is in the fibrous sheath. 111/139 spermatozoa have ectopic fibrous sheath in the midpiece region close to the sperm head.
Specimen 8Ba: postnatal (more )
Note: Double labeled: red - Akap3; green - acrosome.
Structure Level Pattern Image Note
TS28: spermatocyte Present Regionally restricted 8Ba , 8Ba'
Specimen 8Bb: postnatal (more )
Note: Double labeled: red - Akap3; green - acrosome.
Structure Level Pattern Image Note
TS28: spermatocyte Present Regionally restricted 8Bb' , 8Bb Expression is in the fibrous sheath.
Specimen 8Bc: postnatal (more )
Note: Double labeled: red - Akap3; green - acrosome.
Structure Level Pattern Image Note
TS28: spermatocyte Present Regionally restricted 8Bc , 8Bc' Expression is in the fibrous sheath.
Specimen 8Bd: postnatal; Cfap157tm1a(EUCOMM)Hmgu/Cfap157tm1a(EUCOMM)Hmgu (more )
Note: Double labeled: red - Akap3; green - acrosome.
Structure Level Pattern Image Note
TS28: spermatocyte Present Regionally restricted 8Bd' , 8Bd Expression is in the fibrous sheath.
Specimen 8Be: postnatal; Cfap157tm1a(EUCOMM)Hmgu/Cfap157tm1a(EUCOMM)Hmgu (more )
Note: Double labeled: red - Akap3; green - acrosome.
Structure Level Pattern Image Note
TS28: spermatocyte Present Regionally restricted 8Be , 8Be' Expression is in the fibrous sheath.
Specimen 8Bf: postnatal; Cfap157tm1a(EUCOMM)Hmgu/Cfap157tm1a(EUCOMM)Hmgu (more )
Note: Double labeled: red - Akap3; green - acrosome.
Structure Level Pattern Image Note
TS28: spermatocyte Present Regionally restricted 8Bf , 8Bf' Expression is in the fibrous sheath.
Specimen S6Ba: postnatal (more )
Note: Double labeled: red - Akap3; green - acrosome.
Structure Level Pattern Image Note
TS28: spermatocyte Present Regionally restricted S6Ba' , S6Ba Expression is in the fibrous sheath.
Specimen S6Bb: postnatal (more )
Note: Double labeled: red - Akap3; green - acrosome.
Structure Level Pattern Image Note
TS28: spermatocyte Present Regionally restricted S6Bb , S6Bb' Expression is in the fibrous sheath.
Specimen S6Bc: postnatal (more )
Note: Double labeled: red - Akap3; green - acrosome.
Structure Level Pattern Image Note
TS28: spermatocyte Present Regionally restricted S6Bc' , S6Bc Expression is in the fibrous sheath.
Specimen S6Bd: postnatal (more )
Note: Double labeled: red - Akap3; green - acrosome.
Structure Level Pattern Image Note
TS28: spermatocyte Present Regionally restricted S6Bd , S6Bd' Expression is in the fibrous sheath.
Specimen S6Be: postnatal (more )
Note: Double labeled: red - Akap3; green - acrosome.
Structure Level Pattern Image Note
TS28: spermatocyte Present Regionally restricted S6Be' , S6Be Expression is in the fibrous sheath.
Specimen S6Bf: postnatal (more )
Note: Double labeled: red - Akap3; green - acrosome.
Structure Level Pattern Image Note
TS28: spermatocyte Present Regionally restricted S6Bf' , S6Bf Expression is in the fibrous sheath.
Specimen S6Bg: postnatal (more )
Note: Double labeled: red - Akap3; green - acrosome.
Structure Level Pattern Image Note
TS28: spermatocyte Present Regionally restricted S6Bg' , S6Bg Expression is in the fibrous sheath.
Specimen S6Bh: postnatal (more )
Note: Double labeled: red - Akap3; green - acrosome.
Structure Level Pattern Image Note
TS28: spermatocyte Present Regionally restricted S6Bh' , S6Bh Expression is in the fibrous sheath.
Specimen S6Bi: postnatal (more )
Note: Double labeled: red - Akap3; green - acrosome.
Structure Level Pattern Image Note
TS28: spermatocyte Present Regionally restricted S6Bi' , S6Bi Expression is in the fibrous sheath.
Specimen S6Bj: postnatal (more )
Note: Double labeled: red - Akap3; green - acrosome.
Structure Level Pattern Image Note
TS28: spermatocyte Present Regionally restricted S6Bj' , S6Bj Expression is in the fibrous sheath.
Specimen S6Bk: postnatal (more )
Note: Double labeled: red - Akap3; green - acrosome.
Structure Level Pattern Image Note
TS28: spermatocyte Present Regionally restricted S6Bk , S6Bk' Expression is in the fibrous sheath.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory