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Gene Expression Data
Assay Details
Assay
Reference: J:117267 Sarkisian MR, et al., MEKK4 signaling regulates filamin expression and neuronal migration. Neuron. 2006 Dec 7;52(5):789-801
Assay type: Immunohistochemistry
MGI Accession ID: MGI:5812481
Gene symbol: Tbr1
Gene name: T-box brain transcription factor 1
Antibody: anti-Tbr1
Detection system: Secondary antibody
Results
Specimen 1H left: embryonic day 18.5 (more )
Structure Level Pattern Image Note
TS26: cerebral cortex Strong 1H left Expressed by early-born glutamatergic cortical progenitors soon after differentiation and strongly expressed by layer 6 cells.
Specimen 1H right: embryonic day 18.5; Map3k4tm1Flv/Map3k4tm1Flv (more )
Note: slightly enlarged forebrain mutant sample
Structure Level Pattern Image Note
TS26: cerebral cortex Strong 1H right Expressed by early-born glutamatergic cortical progenitors soon after differentiation and strongly expressed by layer 6 cells and numerous cells protruding into the ventricle.
Specimen 1I left: embryonic day 18.5 (more )
Structure Level Pattern Image Note
TS26: forebrain ventricular layer Absent 1I left
Specimen 1I right: embryonic day 18.5; Map3k4tm1Flv/Map3k4tm1Flv (more )
Note: slightly enlarged forebrain mutant sample
Structure Level Pattern Image Note
TS26: forebrain ventricular layer Present Clusters 1I right
Specimen 5F left: embryonic day 17.5 (more )
Note: Double labeled: red - Tbr1; green - Flna (assay MGI:5812525).
Structure Level Pattern Image Note
TS25: cerebral cortex Present 5F left
TS25: cerebral cortex ventricular zone Absent 5F left
Specimen 5F right: embryonic day 17.5; Map3k4tm1Flv/Map3k4tm1Flv (more )
Note: Slightly enlarged forebrain mutant sample. Double labeled: red - Tbr1; green - Flna (assay MGI:5812525).
Structure Level Pattern Image Note
TS25: cerebral cortex Present 5F right
TS25: cerebral cortex ventricular zone Present 5F right
Specimen 5G: embryonic day 17.5; Map3k4tm1Flv/Map3k4tm1Flv (more )
Note: Highly degenerated forebrain mutant sample. Double labeled: red - Tbr1; green - Flna (assay MGI:5812525).
Structure Level Pattern Image Note
TS25: cerebral cortex Present 5G
TS25: cerebral cortex ventricular zone Present 5G
Specimen 5H: embryonic day 17.5; Map3k4tm1Flv/Map3k4tm1Flv (more )
Note: Highly degenerated forebrain mutant sample. Double labeled: red - Tbr1; green - phosphorylated Flna (assay MGI:5812526).
Structure Level Pattern Image Note
TS25: cerebral cortex Present 5H
TS25: cerebral cortex ventricular zone Present 5H
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
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