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Gene Expression Data
Assay Details
Assay
Reference: J:236995 Navein AE, et al., Disrupted mitochondrial function in the Opa3L122P mouse model for Costeff Syndrome impairs skeletal integrity. Hum Mol Genet. 2016 Jun 15;25(12):2404-2416
Assay type: Immunohistochemistry
MGI Accession ID: MGI:5812240
Gene symbol: Opa3
Gene name: optic atrophy 3
Antibody: Anti-Opa3 (15638-1-AP)
Detection system: Secondary antibody coupled to horseradish peroxidase
Results
Specimen 2A: postnatal month 6 (more )
Structure Level Pattern Image Note
TS28: tibia Present Regionally restricted 2A The most pronounced expression was observed in the marrow cavity.
Specimen 2C: postnatal month 6 (more )
Structure Level Pattern Image Note
TS28: tibia Present Regionally restricted 2C Expression was detected in osteoblasts on the endosteal and trabecular surfaces.
Specimen 2E: postnatal month 6 (more )
Structure Level Pattern Image Note
TS28: periosteum Present Regionally restricted 2E Expression was detected on the surface of the cortical periosteum.
TS28: tibia Present Regionally restricted 2E Expression was detected in cortical osteocytes.
Specimen 2G: postnatal month 6 (more )
Structure Level Pattern Image Note
TS28: articular cartilage Present 2G Expression was detected in synovial cartilage.
Specimen 2I: postnatal month 6 (more )
Structure Level Pattern Image Note
TS28: tibia Present 2I Expression was detected in germinal, proliferative, and hypertrophic growth plate chondrocytes.
TS28: bone marrow Present Regionally restricted 2I Expression was detected in adipocytes in the proximal marrow.
Specimen 2K: postnatal month 6 (more )
Structure Level Pattern Image Note
TS28: tibia Present 2K Expression was detected in germinal, proliferative, and hypertrophic growth plate chondrocytes.
TS28: bone marrow Present Regionally restricted 2K Expression was detected in adipocytes in the proximal marrow.
Specimen 2M: postnatal month 6 (more )
Structure Level Pattern Image Note
TS28: bone marrow Present Regionally restricted 2M Expression was detected in mesenchymal stem cell rosettes in the mid-diaphyseal marrow.
Specimen 2O: postnatal month 6 (more )
Structure Level Pattern Image Note
TS28: bone marrow Present Regionally restricted 2O Expression was detected in adipocytes in the distal marrow.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory