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Gene Expression Data
Assay Details
Assay
Reference: J:51645 Mansouri A, et al., Pax3 and Pax7 are expressed in commissural neurons and restrict ventral neuronal identity in the spinal cord. Mech Dev. 1998 Nov;78(1-2):171-8
Assay type: In situ reporter (knock in)
MGI Accession ID: MGI:5810704
Gene symbol: Pax3
Gene name: paired box 3
Reporter: lacZ
Direct Detection
Results
Specimen 4A: embryonic day 10.5; Pax3tm1Pgr/Pax3tm1Pgr (more )
Structure Level Pattern Image Note
TS17: future spinal cord Present Regionally restricted 4A A new LacZ expression pattern was detected in the spinal cord. Expression was observed in fibers originating in the alar plate, elongating ventrally, and crossing the ventral midline (commissural axons).
Specimen 4B: embryonic day 10.5; Pax3tm1Pgr/Pax3tm1Pgr (more )
Structure Level Pattern Image Note
TS17: future spinal cord Present Regionally restricted 4B A new LacZ expression pattern was detected in the spinal cord. Expression was observed in fibers originating in the alar plate, elongating ventrally, and crossing the ventral midline (commissural axons).
Specimen 4D: embryonic day 10.5; Pax3tm1Pgr/Pax3tm1Pgr, Pax7tm2Pgr/Pax7tm2Pgr (more )
Structure Level Pattern Image Note
TS17: future spinal cord Ambiguous Regionally restricted 4D Staining in commissural axons/neurons was not detected.
Specimen 5A: embryonic day 10.5; Pax3tm1Pgr/Pax3tm1Pgr (more )
Structure Level Pattern Image Note
TS17: future spinal cord Present Regionally restricted 5A Expression was detected in the ventral commissure.
Specimen 5C: embryonic day 10.5; Pax3tm1Pgr/Pax3tm1Pgr, Pax7tm2Pgr/Pax7tm2Pgr (more )
Structure Level Pattern Image Note
TS17: future spinal cord Ambiguous Regionally restricted 5C No staining was detected in the ventral commissure.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/18/2025
MGI 6.24 		The Jackson Laboratory