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Gene Expression Data
Assay Details
Assay
Reference: J:195918 Vieux-Rochas M, et al., BMP-mediated functional cooperation between Dlx5;Dlx6 and Msx1;Msx2 during mammalian limb development. PLoS One. 2013;8(1):e51700
Assay type: In situ reporter (knock in)
MGI Accession ID: MGI:5810607
Gene symbol: Dlx5
Gene name: distal-less homeobox 5
Reporter: lacZ
Direct Detection
Results
Specimen 1A: embryonic day 10.5; Dlx5tm1Levi/Dlx5+ (more )
Structure Level Pattern Image Note
TS17: forelimb bud apical ectodermal ridge Present 1A
TS17: forelimb bud mesenchyme Present Scattered 1A Expression only in anterior mesoderm of forelimb.
Specimen 1B: embryonic day 10.5; Dlx5tm1Levi/Dlx5+ (more )
Structure Level Pattern Image Note
TS17: forelimb bud apical ectodermal ridge Present 1B
TS17: forelimb bud mesenchyme Present Regionally restricted 1B Expression only in anterior mesoderm of forelimb.
Specimen 1I: embryonic day 11.5; Dlx5tm1Levi/Dlx5+ (more )
Structure Level Pattern Image Note
TS19: handplate apical ectodermal ridge Present 1I
TS19: forelimb bud mesenchyme Present Regionally restricted 1I Expression only in anterior mesoderm of forelimb.
Specimen 1J: embryonic day 11.5; Dlx5tm1Levi/Dlx5+ (more )
Structure Level Pattern Image Note
TS19: handplate apical ectodermal ridge Present 1J
TS19: handplate mesenchyme Present Regionally restricted 1J Expression only in anterior mesoderm of forelimb.
Specimen 1O: embryonic day 10.5; Dlx5tm1Levi/Dlx5+ (more )
Structure Level Pattern Image Note
TS17: hindlimb bud apical ectodermal ridge Present 1O
TS17: hindlimb bud mesenchyme Absent 1O No expression in anterior hindlimb mesoderm.
Specimen 1P: embryonic day 10.5; Dlx5tm1Levi/Dlx5+ (more )
Structure Level Pattern Image Note
TS17: hindlimb bud apical ectodermal ridge Present 1P
TS17: hindlimb bud mesenchyme Absent 1P No expression in anterior hindlimb mesoderm.
Specimen 1W: embryonic day 11.5; Dlx5tm1Levi/Dlx5+ (more )
Structure Level Pattern Image Note
TS19: footplate apical ectodermal ridge Present 1W
TS19: hindlimb bud mesenchyme Present Regionally restricted 1W Expression in mesoderm starts around E11.5 and in confined to the anterior margin.
Specimen 1W': embryonic day 11.5; Dlx5tm1Levi/Dlx5+ (more )
Structure Level Pattern Image Note
TS19: footplate apical ectodermal ridge Strong 1W'
Specimen 1W": embryonic day 11.5; Dlx5tm1Levi/Dlx5+ (more )
Structure Level Pattern Image Note
TS19: footplate apical ectodermal ridge Strong 1W"
TS19: footplate mesenchyme Weak Regionally restricted 1W" Weak expression in anterior mesoderm.
Specimen 1X: embryonic day 11.5; Dlx5tm1Levi/Dlx5+ (more )
Structure Level Pattern Image Note
TS19: footplate apical ectodermal ridge Present 1X
TS19: footplate mesenchyme Present Regionally restricted 1X Expression in mesoderm starts around E11.5 and in confined to the anterior margin.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/18/2025
MGI 6.24 		The Jackson Laboratory