About   Help   FAQ
Gene Expression Data
Assay Details
Assay
Reference: J:59282 Yi SE, et al., The type I BMP receptor BMPRIB is required for chondrogenesis in the mouse limb. Development. 2000 Feb;127(3):621-30
Assay type: RNA in situ
MGI Accession ID: MGI:5806660
Gene symbol: Sox9
Gene name: SRY (sex determining region Y)-box 9
Probe: Sox9 cDNA19
Probe preparation: Antisense RNA
Results
Specimen 3a Wild type: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: forelimb digit Strong Regionally restricted 3a wild type Highest expression was found in the region of the future terminal phalanges and lower expression was found in the region of the metacarpal/phalangeal joint.
Specimen 3a BmprIB-/-: embryonic day 12.5; Bmpr1btm1Kml/Bmpr1btm1Kml (more )
Structure Level Pattern Image Note
TS20: forelimb digit Strong Regionally restricted 3a BmprIB-/- No differences in expression were found in the mutant.
Specimen 3b Wild type: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: forelimb digit Strong Regionally restricted 3b wild type Highest expression was detected in the distal cells of the digital ray. Moderate levels persist in the phalangeal region.
TS21: forelimb interphalangeal joint Strong Regionally restricted 3b wild type Highest expression was detected in the future interphalangeal joint.
Specimen 3b BmprIB-/-: embryonic day 13.5; Bmpr1btm1Kml/Bmpr1btm1Kml (more )
Structure Level Pattern Image Note
TS21: forelimb digit Weak Regionally restricted 3b BmprIB-/- In the mutant, expression was markedly reduced in the presumptive phalanges and there is no evidence of interphalangeal joint formation.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
05/07/2024
MGI 6.23 		The Jackson Laboratory