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Gene Expression Data
Assay Details
Assay
Reference: J:14491 Dolle P, et al., Local alterations of Krox-20 and Hox gene expression in the hindbrain suggest lack of rhombomeres 4 and 5 in homozygote null Hoxa-1 (Hox-1.6) mutant embryos. Proc Natl Acad Sci U S A. 1993 Aug 15;90(16):7666-70
Assay type: RNA in situ
MGI Accession ID: MGI:5805917
Gene symbol: Hoxb2
Gene name: homeobox B2
Probe: Hox-2.8 probe1
Probe preparation: Antisense RNA
Visualized with: Autoradiography
Results
Specimen 1a: embryonic day 8.5 (more )
Structure Level Pattern Image Note
TS13: embryo mesenchyme Present 1a b-2
TS13: rhombomere 3 Present 1a b-2
TS13: rhombomere 4 Present 1a b-2
TS13: rhombomere 5 Present 1a b-2
TS13: rhombomere 2 Absent 1a b-2
Specimen 1b: embryonic day 8.5; Hoxa1tm1Ipc/Hoxa1tm1Ipc (more )
Structure Level Pattern Image Note
TS13: embryo mesenchyme Present 1b b-2 Expression in this mutant is the same as in wild-type.
TS13: rhombomere 3 Present 1b b-2 Expression in this mutant is the same as in wild-type.
TS13: rhombomere 4 Present 1b b-2 Expression in this mutant is the same as in wild-type.
TS13: rhombomere 5 Present 1b b-2 Expression in this mutant is the same as in wild-type.
TS13: rhombomere 2 Absent 1b b-2
Specimen 2d: embryonic day 9.5 (more )
Structure Level Pattern Image Note
TS15: facio-acoustic preganglion complex Present 2d b-2
Specimen 2e: embryonic day 9.5; Hoxa1tm1Ipc/Hoxa1tm1Ipc (more )
Structure Level Pattern Image Note
TS15: facio-acoustic preganglion complex Present 2e b-2 Expression was disorganized in this mutant as a narrow stripe adjacent and parallel to the neuroepithelium at the level of the otocyst.
Specimen not shown E8.5-/-: embryonic day 8.5; Hoxa1tm1Ipc/Hoxa1tm1Ipc (more )
Structure Level Pattern Image Note
TS13: embryo Present Expression in posterior regions of the mutant embryo is the same as in wild-type.
Specimen not shown E9.5-/-: embryonic day 9.5; Hoxa1tm1Ipc/Hoxa1tm1Ipc (more )
Structure Level Pattern Image Note
TS15: embryo Present Expression in posterior regions of the mutant embryo is the same as in wild-type.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/18/2025
MGI 6.24 		The Jackson Laboratory